Today's common chemotherapy drug side effects are dealt with, let's talk about etoposide. If you like this article, please like, comment, and share, this is the motivation for us to continue to popularize science.
Etoposide is one of the most commonly used chemotherapy drugs for small cell lung cancer and is usually used for 3-5 days.
1. Indications for etoposide
Small cell lung cancer, malignant lymphoma.
Second, the effect of etoposide drugs
Etoposide, a genocidoxin derivative, belongs to cell cycle-specific antitumor drugs. It mainly acts on cellular DNA, hinders DAN repair and thus exerts anti-tumor effects.
3. The most common side effects of etoposide
1. Hematotoxic reactions: including leukopenia, thrombocytopenia, bleeding and anemia;
2. Digestive system toxicity: nausea, vomiting, loss of appetite, abdominal pain, diarrhea, constipation, etc. may occur;
3. Allergic reactions: such as rash, erythema, itching;
4. Hepatorenal toxicity: cause elevation of aminotransferase, bilirubin, alkaline phosphatase and urea nitrogen;
5. Digestive system toxicity: sometimes nausea and vomiting, loss of appetite, stomatitis, diarrhea and constipation;
6. Others: sometimes fatigue and fatigue.
4. Prevention of side effects of etoposide
1. It cannot be injected subcutaneously or intramuscularly, which is easy to cause local necrosis;
2. It is easy to cause hypotension, and the infusion process needs to be slow when changing the position;
3. The patient's blood picture should be checked regularly during the medication.
5. Dietary precautions
1. During chemotherapy, animal protein intake should be the mainstay, such as chicken, duck, fish, meat, eggs, and milk, to ensure daily energy and protein intake;
2. Reference to the order of dining: soup - > vegetables - > meat dishes - > staple food to increase nutritional intake.
6. Supplement medical nutrients to prevent side effects
If you have poor physical constitution and low immunity, you can supplement glutathione precursors to prevent bone marrow suppression (leukopenia, thrombocytopenia, anemia) before taking drugs;
Illustration of related research
Clinical and research studies have shown that improving the gut microbiota can avoid gastrointestinal reactions such as diarrhea, constipation and bloating, and it is also valuable for chemotherapy patients to balance the gut microbiota and reduce adverse effects.
Screenshot of related research
Why these two nutrients? During chemotherapy, nausea and vomiting require digestive enzymes to help with digestion.
It should be noted that digestive enzymes should be selected, and they contain protease, amylase and lipase in order to digest all kinds of food.
Clinical and research studies have shown that fish oil can not only reduce inflammation, but also improve nausea and vomiting, but the Omega-3 content in fish oil must reach more than 90% for obvious effects.
Therefore, digestive enzymes and fish oil can be supplemented in advance to prevent loss of appetite, nausea and vomiting.
These two nutrients can be used to prevent chemotherapy-induced stomatitis (canker sores, oral mucositis).
Studies have shown that fish oil Omega-3 can interfere with the synthesis of inflammatory cytokines, have anti-inflammatory effects, and can improve patients' appetite, food intake, lean body mass, and body weight.
Vitamin B12 can repair DNA molecules, promote wound mucosa, significantly increase the pain threshold in the hyperalgesic area, have obvious local analgesic effect, and at the same time, prevent difficulty in opening the mouth. The best effect is vitamin B12 at a dose of 5000mcg/capsule, taken sublingually (saliva is absorbed faster than the gastrointestinal tract).
Finally, I hope you can successfully complete chemotherapy, and you can also click below to learn about other side effects of chemotherapy drugs related to etoposide and how to deal with them.
How to deal with the common side effects of carboplatin, please collect it for cancer patients
How to deal with the common side effects of cisplatin, please collect it for cancer patients
Cyclophosphamide (ifosfamide) common side effects coping methods, cancer patients please bookmark
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There are many dangers on the road to fight cancer, but the danger does not stop us from moving forward, once there is a problem, communicate with the doctor in time, do not believe in the home remedies, firmly believe in standardized treatment, you are not alone on the road to fight cancer, I am a doctor with health, I hope to help you!