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Clinical perspectives on various neuromodulation therapies for OAB in Europe

author:Medical Mirrors

Dick AW. of the Netherlands Professor Janssen writes about a variety of well-established and experimental electrical nerve stimulation therapies for the treatment of lower urinary tract dysfunction.

The article discusses and analyzes various clinical treatments that have been recognized, including percutaneous tibial nerve stimulation therapy (PTNS), percutaneous electrical nerve stimulation (TENS), sacral nerve stimulation therapy (SNS), and anterior sacral nerve root stimulation (SARS). In addition, some experimental clinical treatment options, such as dorsal genital nerve (DGN) stimulation, pudendal nerve stimulation, neuromagnetic stimulation, and ankle implantation tibial nerve stimulation, were also analyzed and evaluated.

Clinical perspectives on various neuromodulation therapies for OAB in Europe

Dick AW. Professor Janssen's article points out that there have been many studies that have demonstrated the significant efficacy of SNM and P-PTNS in overactive bladder disease (OAB). SARS has a certain effect on spinal cord nerve patients and can improve the quality of life of patients. TENS is less effective than other OAB treatments (e.g., SNS therapy and P-PTNS therapy), but it is less invasive and can be treated on an outpatient basis. Some experimental therapies, such as pudendal nerve stimulation, appear to have a good prognosis, but large clinical follow-up studies are needed to screen out the placebo effect.

Clinical perspectives on various neuromodulation therapies for OAB in Europe
Clinical perspectives on various neuromodulation therapies for OAB in Europe
Clinical perspectives on various neuromodulation therapies for OAB in Europe

At present, it can be confirmed that the efficacy of various nerve stimulation is better in the treatment of refractory bladder dysfunction.

----JanssenD A, Martens F M, de Wall L L, et al. Clinical utility of neurostimulationdevices in the treatment of overactive bladder: current perspectives. [J]. Medical Devices, 2017, 10:109-122.