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What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

author:Dr. Zeng is a general practitioner of internal medicine
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In daily life, many people tend to ignore the early warning signs sent by the body, thinking that these uncomfortable symptoms are just minor problems and not worth making a fuss about. However, ignoring these symptoms can lead to exacerbations and even life-threatening conditions. This article will detail 8 symptoms that doctors recommend not to ignore to help you better recognize and respond to your body's early warning signs.

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

The importance of early identification and management of acute illness

Early recognition of acute severe disease is critical because the inflammatory response has multiple redundant pathways that, once out of control, can rapidly spread throughout the body, leading to severe organ failure.

According to studies at Norfolk and Norwich University Hospitals in the UK, 27% of ICU patients present with severe sepsis within the first 24 hours of admission, and these patients have a follow-up in-hospital mortality rate of up to 47%. This suggests that mortality can be significantly reduced if effective management measures are taken early in the inflammatory response.

The inflammatory response typically involves activation of the innate immune system and includes both soluble (e.g., complement system, acute-phase proteins, and cytokines) and cellular components (e.g., monocytes, macrophages, neutrophils, dendritic cells, and natural killer cells).

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

These responses can be triggered by necrotic and apoptotic cells, as well as by exogenous proteins. If this response is out of local control, clinical manifestations include systemic inflammatory response syndrome (SIRS) and multi-organ dysfunction (MOD).

Systemic inflammatory response syndrome is a key indicator of severe disease and is common in the setting of infection, trauma, etc. Studies have shown that 27% of patients admitted to the intensive care unit (ICU) show severe sepsis within the first 24 hours of admission, and these patients have an in-hospital mortality rate of 47%. These data demonstrate the importance of early identification and intervention.

The importance of an early warning scoring system

To identify and manage severe disease, many hospitals have adopted an early warning scoring system. These scoring systems are based on abnormalities in heart rate, blood pressure, respiratory rate, body temperature, and level of consciousness.

At Norfolk and Norwich University Hospitals, the threshold for the Early Warning Scoring System is set at 3 points. By monitoring these physiological parameters, the scoring system helps medical staff identify potentially critically ill patients in a timely manner.

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

Respiratory rate is one of the most sensitive indicators in the early warning scoring system. Studies have shown that changes in respiratory rate are often an early signal of worsening disease.

If the respiratory rate increases, it may signal an exacerbation and requires immediate intervention. These systems help healthcare professionals identify and deal with potential crisis situations in a timely manner by monitoring parameters such as respiratory rate, heart rate, and blood pressure.

Eight symptoms that cannot be ignored

Rapid breathing

Shortness of breath is an important early symptom that may indicate a problem with the respiratory or cardiovascular system. Shortness of breath is not just a sign of physical fatigue, it can be a sign of a more serious health problem. If you notice that you or someone close to you is experiencing shortness of breath, don't take it lightly, and timely medical attention is key.

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

Persistent high fever

A high fever is the body's response to an infection, but if it persists, it can be a sign of a serious infection or other illness. A high fever is not only uncomfortable, but it can also have serious effects on the body. If you have a persistent high fever, you should go to the hospital as soon as possible for a detailed examination to find out the cause and treat it.

Chest pain

Chest pain can be an early sign of a heart attack. Even mild discomfort should not be ignored, especially if accompanied by symptoms such as sweating and nausea. The consequences of a heart attack can be very serious, and timely medical intervention can save lives.

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

Persistent headaches

Frequent or persistent headaches may be a manifestation of brain disorders or high blood pressure. In particular, if you have a sudden, severe headache, you need to seek medical attention as soon as possible. Not only does headache affect quality of life, but it can also be a harbinger of a more serious illness and should not be taken lightly.

stomach ache

Abdominal pain can be caused by a variety of causes, including gastrointestinal disorders, kidney stones, etc. If abdominal pain is severe or prolonged, prompt testing is needed to rule out serious problems. Abdominal pain can be a hint of a problem with the internal organs, and early detection and treatment are very important.

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

Sudden changes in vision

A sudden change in vision can be a sign of a stroke or other neurological disorder. Changes in vision should not be ignored and should be sought immediately. A sudden change in vision can be an urgent signal from the body that requires a quick response and processing.

Unexplained weight loss

Significant weight loss without weight loss may be a sign of a serious illness such as endocrine disorders and cancer. Tests should be done as soon as possible to find out the cause. Unexplained weight loss can be a sign of a problem with the body's internal systems, and timely medical check-ups can detect and treat the underlying disease early.

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

Persistent fatigue

Long-term fatigue can be a manifestation of chronic diseases such as diabetes, thyroid disease, etc. A thorough examination should be performed to determine the cause. Persistent fatigue not only affects quality of life, but can also suggest the presence of a chronic illness that needs to be taken seriously and examined.

Early management strategies

Early management is key to preventing the condition from getting worse. With timely medical intervention, the chain reaction of organ failure can be prevented and the survival rate of patients can be improved. Goal-directed therapy improves the matching of systemic oxygen delivery to demand by optimizing cardiac preload, afterload, and contractility. Studies have shown that early goal-directed therapy significantly reduces mortality in severely ill patients.

What are the precursors of illness? Doctor: 8 symptoms recommend not to "carry hard"

A study at Norfolk and Norwich University Hospitals showed a significant increase in mixed venous oxygen saturation, a decrease in lactate levels, a decrease in APACHE II scores, and a significant reduction in in-hospital mortality in patients treated with early goal-directed therapy. This suggests that early identification and management of disease precursors is essential to improve patient survival.

The core of goal-oriented therapy is to monitor and adjust the patient's cardiopulmonary function parameters to achieve optimal performance, so as to improve the efficiency of oxygen delivery and meet the body's needs. This approach not only improves the patient's short-term health, but also significantly reduces the risk of long-term complications.

conclusion

Early identification and management of the precursors of disease is essential to improve patient survival. By employing an early warning scoring system and timely interventions, healthcare workers can effectively prevent and manage potentially severe cases. Hopefully, the eight symptoms introduced in this article will help you better pay attention to your health and take timely measures to prevent minor illnesses from becoming major ones.

Finally, what experiences and insights would you like to share? Feel free to leave a message in the comment area!

Bibliography:

1. Saxon Ridley, "The recognition and early management of critical illness," Annals of The Royal College of Surgeons of England, 2005, 87: 315-322.

2. A. Padkin, C. Goldfrad, A.R. Brady, D. Young, N. Black, K. Rowan, "Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland," Critical Care Medicine, 2003, 31: 2332-2338.