Recently, Bloomage Biotech's world's largest pilot transformation platform in Tianjin was fully completed, and its Biomanufacturing 5.0 Science and Technology Museum was officially opened. With the theme of "Biomanufacturing, Creating an Infinite Future", the exhibition hall is the world's first science and technology museum in the field of biomanufacturing, which comprehensively introduces the evolution of biomanufacturing from 1.0 to 5.0, and presents the promotion and contribution of biotechnology development to the sustainable development of resources and the environment.
Industry insiders believe that the biomanufacturing 5.0 era, which deeply integrates synthetic biotechnology and artificial intelligence, will lead biomanufacturing into a new stage of exponential rapid growth. The exhibition hall not only comprehensively demonstrates the development process of the biomanufacturing industry and provides a social cognitive foundation for promoting the development of new quality productivity, but also an important innovation in Bloomage Biotech's ESG practice.
Firmly adhere to the path of green technology for biomanufacturing, and promote the implementation of sustainable development
At present, environmental problems such as global warming, frequent natural disasters, and loss of biodiversity have become major problems restricting the development of human society. Exploring the root cause of this is not the development of science and technology itself, but the fact that we have not yet found a green and sustainable path for the development of science and technology.
Biomanufacturing is the key to solving this problem. It subverts the traditional way of obtaining resources through animal and plant extraction and petrochemical industry, and its application in the production process can significantly reduce waste generation and environmental damage, improve resource utilization efficiency, and lead us to a more intelligent, efficient and environmentally friendly new future.
The "2024 Government Work Report" will "accelerate the development of new quality productivity" as the primary task in 2024, and emphasize actively cultivating emerging industries and future industries, and actively building new growth engines such as biomanufacturing, commercial aerospace, and new materials, among which biomanufacturing ranks first.
However, despite the great potential of biomanufacturing, it still faces serious challenges in industrial transformation. Industry insiders pointed out that although theoretically more than 60% of the world's important chemicals, fuels, natural products and raw materials can be obtained through biosynthesis, less than 6% of the actual biosynthetic manufacturing is realized. This huge digital divide highlights the severe challenges faced by synthetic biotechnology between scientific research achievements and industrial transformation, and enterprises with strong industrial transformation capabilities are urgently needed to lead the breakthrough.
As an indispensable process to turn biotechnology into productivity, the pilot transformation platform has played a key role in solving this problem. The Biomanufacturing 5.0 Science and Technology Museum shows that Bloomage Biotech is establishing a whole industry chain cooperation model with the vision of "Future Imagination - Synthetic Biology R&D - Process Development - Pilot Scale Up - Process Verification - Industrial Production - Commercial Application", aiming to provide efficient and reliable process support and comprehensive solutions for the transformation of technological achievements. Through biomanufacturing, upstream R&D, midstream manufacturing and downstream product development can be connected, and an industrial ecological closed loop can be built together.
Bloomage Biotech has demonstrated with practical actions how Chinese enterprises can promote ESG concepts through scientific and technological innovation throughout the whole process of enterprise production and operation. This innovative initiative is expected to disrupt traditional manufacturing methods and is expected to reduce carbon emissions by more than 50% in the future, contributing to global sustainable development.
Innovate the dual drive of "technology + exhibition hall" to lead the green development of the industry
"Promoting the deep integration of scientific and technological innovation and industrial innovation, and strengthening the main position of enterprises in scientific and technological innovation" has become a key guideline for promoting high-quality development. As a leading enterprise in the whole industry chain of biotechnology and biomaterials, Bloomage Biotech continues to lead and promote sustainable development with scientific and technological innovation, and actively undertakes the mission of science popularization for the public, and has achieved fruitful ESG practices.
Take hyaluronic acid, for example. In the four industrial revolutions in the field of hyaluronic acid, Bloomage Biotech has led the last three, and has successively improved resource utilization efficiency through technological innovations such as "microbial fermentation", "enzymatic digestion" and "synthetic biotechnology", thereby promoting the development of new quality productivity and promoting the realization of ESG goals.
In the early days, the industry mainly obtained hyaluronic acid through animal extraction methods (chicken comb, umbilical cord), and only 1 kg of hyaluronic acid could be extracted from 200 kg of chicken comb, which not only had extremely low extraction efficiency, but also only 50%-60% of product purity, and produced a lot of resource consumption and carbon emissions; In the 90s of the last century, Bloomage Biotech realized the large-scale production of hyaluronic acid by microbial fermentation, which greatly improved the production efficiency and product quality of hyaluronic acid, and reduced energy consumption and resource consumption; In 2012, Bloomage Biotech realized the world's first large-scale production of oligomeric hyaluronic acid by enzymatic digestion, further improving product quality, reducing costs and increasing efficiency, and promoting the upgrading and development of the hyaluronic acid industry.
In order to better popularize the science of how scientific and technological innovation can empower the sustainable development of the industry to the public, in 2020, Bloomage Biotech built the World Hyaluronic Acid Museum in Jinan, Shandong Province, to present the development history of the mainland hyaluronic acid industry in an all-round way. As of December 2023, the World Hyaluronic Acid Museum has received a total of 27,692 visitors.
In 2018, Bloomage Biotech anchored synthetic biology, a global cutting-edge technology, and further promoted the sustainable development driven by science and technology. Through synthetic biotechnology, Bloomage Biotech has achieved a hyaluronic acid laboratory fermentation yield of more than 73g/L, which is more than 4 times that of the original. The increase in yield can not only reduce the consumption of energy and starch materials by 60%-75%, but also reduce the carbon emissions in the production process by 35%-65%.
It can be said that the history of the hyaluronic acid industry promoted by Bloomage Biotech is also the revolutionary history of green production methods. In particular, synthetic biology is produced through cell factories, which is more efficient, low-carbon and environmentally friendly than traditional production methods, meets the requirements of the development of new quality productivity, and is an important underlying support for achieving the strategic goals of "carbon peak" and "carbon neutrality". Zhao Yan, Chairman of Bloomage Biotech, said, "Synthetic biology is in line with the requirements of sustainable development, the strategic direction of the country, the development trend of biotechnology, and the development path of the enterprise, which is the inevitable choice of Bloomage Biotech. ”
At present, Bloomage Biotech has become one of the few synthetic biology industry chain companies in China that integrates the three forces of "R&D innovation, pilot test, industrial transformation, and market transformation", and has continuously launched innovative achievements and successfully implemented them. In August 2022, Bloomage Biotech completed the world's first synthetic biology science museum, showing how synthetic biology can reshape the earth's resources. Through social science education, more people can recognize the role of synthetic biology as a green technology in promoting sustainable development. In addition, according to the 2023 annual report, Bloomage Biotech has carried out 132 R&D projects of raw materials and synthetic biology, and has listed raw material products such as ultra-pure ergothioneine, micro-truth, recombinant type III humanized collagen, lipopeptides, etc., and has completed the pilot test of salidroside, carnosine, and human milk oligosaccharides.
Obviously, scientific and technological innovation is a key element in shaping new quality productivity and achieving sustainable development. Under the global wave of ESG, Bloomage Biotech stands at the forefront of industry development with its innovative achievements in the field of biomanufacturing, and promotes the development of biomanufacturing industry to the 5.0 era with the strong driving force of scientific and technological innovation, and at the same time enhances the public's awareness of the biomanufacturing industry through social science education, enhances the society's consensus on sustainable development goals, and paves a green development path for a better life.