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Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

author:Market Information Newspaper New Media

The special season of "Great Chinese Ingredients" initiated by Giant Engine was officially announced, and the exclusive patented ingredient of double bacteria and double fermentation - TIRACLE PRO, which has been researched by Han Shu for ten years, was unveiled, which is also the second time that Han Shu has won this award after "Cyclohexapeptide-9" was selected last year.

Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

As a special season of the "Great Chinese Ingredients" IP campaign, this season will focus on the theme of "Great Chinese Ingredients, Rejuvenate Chinese Brands", and delve into the story of "ingredients" and broaden the value of "ingredients".

Han Shu's ingenuity in grinding a sword for ten years, and Han Shu's determination to devote more than 21 years of independent research to independent research are the best proof of the symbiosis and co-prosperity of Chinese ingredients and Chinese brands.

Twice selected,

Just to prove that the Chinese ingredient is amazing

This is the second time that Han Shu has been selected for the "Great Chinese Ingredients", and in 2023, Han Shu's exclusive ingredient "Cyclohexapeptide-9" won this award for its uniqueness, innovation and breakthrough in efficacy.

According to Han Shu, the selected ingredient TIRACLE PRO is a "small molecule peptide cluster" containing 2,836 kinds of small molecule peptides after the screening of more than 350 strains and more than 110 process screenings, using the unique double bacteria (thermophilus + bacillus) double fermentation technology, and refining through the secondary fermentation process, which has the effect of stimulating autophagy, promoting osmosis, and rejuvenating and rejuvenating.

Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

In addition to the superiority of efficacy, the more far-reaching significance is that TIRACLE PRO is also a solid self-developed and original ingredient of a Chinese brand. ACCORDING TO THE DATA, TIRACLE PRO IS THE FIRST BASIC RESEARCH ACHIEVEMENT OF SHANGMEI, AND IT IS ALSO AN IMPORTANT STEP FOR INDEPENDENT AND EXCLUSIVE RAW MATERIALS DEVELOPED FROM 0 TO 1, LEADING DOMESTIC BRANDS TO BREAK THROUGH THE MONOPOLY OF INTERNATIONAL RAW MATERIALS.

"To catch up with the distance opened 100 years ago, brands can only rely on pragmatic precipitation, exploration, and breakthrough." Liu Ming, vice president of Shangmei Co., Ltd., the parent company of Han Shu, revealed the hardships and dedication behind the skin rejuvenation.

In fact, it is not difficult to make an excellent ingredient, but it is not easy to make an excellent Chinese ingredient, because Chinese ingredient cannot step on the footprints of existing popular ingredients to make secondary innovations, and must step out of its own way to achieve transcendence.

"Without relying on the purchase of raw materials, breaking the monopoly of raw materials of foreign suppliers, we can only rely on our own ingredient patents and raw materials to occupy the highland of scientific research." In the tracing of the origin of the rejuvenating cause of "Great Chinese Ingredients", Dr. Huang Hu, CTO and global chief scientist of Shangmei Co., Ltd., revealed that Shangmei Co., Ltd. has always set a red line for research and development - not imitation, but innovation.

Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

In the past, self-research has always been the shortcoming of domestic skin care, only by building up the highland, in order to achieve the real height of Chinese ingredients, now Chinese brands must have a faster iteration speed than foreign brands, truly independent research and development, continue to upgrade raw materials and formulas, in order to break the more and more "volume" of the beauty market, truly meet the skin care needs of consumers.

Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

The uniqueness and superiority of Chinese ingredients have allowed Han Shu to usher in a new round of potential energy explosion in recent years, from the trough of the brand to the head of the industry, which is the best feedback from the market to Chinese ingredients.

The fact that the rejuvenating skin has been successfully verified by the market further meets everyone's expectations that Chinese ingredients are "amazing".

10 years of "rejuvenating causes"

There is no shortcut to the breakthrough of the Chinese component

THE RESEARCH OF TIRACLE PRO IS NOT ACHIEVED OVERNIGHT, BUT IS THE RESULT OF MORE THAN 20 YEARS OF PEPTIDE RESEARCH BY HAN SHU. Since its inception, Han Shu has begun the research and application of "peptide field", the history of Han Shu brand for more than 20 years, is also a collection of world scientific research, breaking the monopoly of international raw material suppliers, from the understanding of peptides, analysis of peptides, application of peptides to the process of innovative peptides.

BEHIND THE BIRTH OF TIRACLE PRO, IT IS HAN SHU WHO CONTINUES TO PROMOTE THE RESEARCH OF "PEPTIDE" RAW MATERIALS WITH THE IDEA OF BIOLOGICAL FERMENTATION, AND FINALLY OBTAINS A "SMALL MOLECULE PEPTIDE CLUSTER" WITH MORE COMPREHENSIVE EFFICACY THROUGH THE FERMENTATION PROCESS.

In the field of beauty research, fermentation is not a technology with a high threshold, but it is easy to get started, but it is difficult to achieve sophistication.

According to the "FBeauty Future Trace", the basic fermentation process is not difficult to achieve, but limited by the past technology, fermentation from strain selection, transformation to mass production engineering control needs to be tackled layer by layer, and at the same time, the analysis of a variety of functional ingredients in fermentation ingredients, and the verification and safety evaluation of their pathways and targets are very complex.

Because of this, in the past, there were many fermented ingredients in the beauty market, but few unique core ingredients appeared, and it was even more difficult to make a Chinese ingredient with leading performance on the path of fermentation. And Han Shu has explored his own path from scratch on this road.

As early as 2017, Han Shu established a dual-bacteria fermentation platform, officially started the research and development of dual-bacteria fermentation ingredients with independent technology, and carried out full-link basic research on strain screening, fermentation process, and component mechanism properties, compared with the fermentation of single thermophilic thermobacteria and bacillus fermentation, the protease productivity of the double-bacteria fermentation process increased by about 130% and 328% respectively.

Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

Han Shu has issued a number of process patents in the process development of improving the fermentation efficiency of double bacteria and improving the fermentation bubbles

There is never a shortcut to quality, and there is no shortcut to Chinese ingredients.

Han Shu has issued a number of process patents in the process development of improving the fermentation efficiency of double bacteria and improving the fermentation bubbles.

AFTER YEARS OF UNREMITTING RESEARCH, HAN SHU HAS DEVELOPED THE PREDECESSOR OF TIRACLE PRO - THE FIRST TIRACLE. This achievement has been approved for invention patents in China, Japan and other places, and has been released on many international technology platforms such as IFSCC (International Federation of Cosmetic Chemists), 2019 SID (Society of Investigative Dermatology) conference, 2019-JCD (Journal of Cosmetic Dermatology) conference.

But Han Shu didn't stop there.

IN THE FOLLOWING THREE YEARS, HAN SHU CONTINUED TO PROMOTE THE RESEARCH OF "PEPTIDE" RAW MATERIALS WITH THE IDEA OF BIOLOGICAL FERMENTATION, CONTINUED TO SCREEN MORE THAN 350 STRAINS AND MORE THAN 110 PROCESS SCREENINGS, AND REPLACED THE SAKE YEAST IN THE ORIGINAL TIRACLE WITH BACILLUS.

MORE THAN 110 PROCESS SCREENINGS HAVE LED TO THE EVOLUTION OF TIRACLE PRO. TIRACLE PRO is rich in 2,836 kinds of peptides, polyphenols, polyamines, amino acids and other substances, and through the small molecule peptide cluster operation, the production capacity has the effect of stimulating autophagy, promoting penetration, and rejuvenating and rejuvenating.

MORE IMPORTANTLY, AT THE LEVEL OF EFFICACY VERIFICATION, TIRACLE PRO FURTHER CRACKS THE "BLACK BOX" OF FERMENTED INGREDIENTS, SO THAT THE COMPOSITION MECHANISM OF FERMENTED INGREDIENTS CAN BE EXPLAINED CLEARLY AND CLEARLY.

THE OMICS ANALYSIS OF THE ACTIVE SUBSTANCES IN TIRACLE PRO SHOWED THAT THE ACTIVE SUBSTANCES IN THE FERMENTATION PRODUCTS WERE INVOLVED IN VARIOUS PROCESSES INCLUDING BIOFUSION, BIOLOGICAL REGULATION, ANTIOXIDANT ACTIVITY, BINDING, DETOXIFICATION, LOCALIZATION, EXERCISE, METABOLIC PROCESS, AND STIMULUS RESPONSE.

EXPERIMENTS HAVE PROVED THAT TIRACLE PRO CAN SIGNIFICANTLY INCREASE THE EXPRESSION OF OCLN, SDC1 AND HSPG2 GENES IN KERATINOCYTES, AND CAN ENHANCE THE DERMAL EPIDERMAL JUNCTION LAYER OF THE SKIN, AND THE EFFICACY IS COMPARABLE TO RHAMNOSE.

It is worth noting that due to the high permeability of small molecule peptides, TIRACLE PRO can directly act on the deep layers of the skin to improve skin problems caused by aging or external environmental factors.

In this regard, Dr. Huang Hu said: "IN THE DEVELOPMENT AND APPLICATION OF PEPTIDE INGREDIENTS, TIRACLE PRO HAS REACHED A NEW LEVEL. ”

With the ingenuity and determination to sharpen a sword for ten years, from strain screening to process breakthroughs, to efficacy verification, Han Shu has gone through every step steadily, allowing Han Shu to develop TIRACLE PRO, a masterpiece of Chinese ingredients.

Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

Research 3.0

With 20+ years to play the confidence of Chinese ingredients

R&D has always been a slow and meticulous thing.

However, in order to catch up with the century-old scientific research gap in just a few decades, Chinese ingredients need not only hard work, but also the determination and courage to compete with international brands through independent research and development of core ingredients.

In just 20 years of development, Shangmei has completed the triple jump in scientific research and entered the scientific research 3.0 stage of "innovation and transcendence", based on AI big data, with cutting-edge computational biology research as the core, open innovation as the path, consolidating basic research, independently developing exclusive raw materials, and empowering product quality upgrades. Set the world's scientific research, serve Chinese brands, and serve Chinese consumers.

AT THE SAME TIME, SHANGMEI HAS ALSO BUILT A MATURE TALENT AND TECHNOLOGY SYSTEM, AND HAS ACCUMULATED A NUMBER OF SCIENTIFIC RESEARCH ACHIEVEMENTS SUCH AS CYCLOHEXAPEPTIDE-9, TIRACLE PRO, E-AGSE, AND Artemisia annua OIL AN+.

Rooted in the victory of scientific anti-aging, Han Shu rejuvenated skin for its appearance as a "great Chinese ingredient"

In this process, Shangmei has also worked with relevant industry departments and associations to formulate and release a number of industry group standards, such as "Synthetic Peptides for Cosmetic Raw Materials", "Group Standards for Olive Leaf Extract for Cosmetic Raw Materials" and "Efficacy Evaluation of Skin Microecological Regulating Cosmetics", becoming a leader in industry technology.

Behind the applause and achievements is the firm investment of domestic beauty companies in research and development.

With more than 20 years of R&D exploration and continuous investment in scientific research, Shangmei has established 2 R&D centers around the world, allowing Chinese R&D and Chinese ingredients to show their strength. The spirit of Chinese ingredients not admitting defeat and Han Shu's never-stop pace make the four words of Chinese ingredients more weighty.

Nowadays, the development pattern of the global skin care industry is undergoing a great change.

The breakthrough of Chinese ingredients represented by SkinActivate, and the independent research and development of the whole chain from basic research to product application, are breaking the technical barriers of international brands in high-end cosmetic ingredients.

But more importantly, in the increasingly fierce market competition, these remarkable Chinese ingredients have further strengthened consumers' confidence in domestic brands.

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