In a laboratory at Chemtura in the United States, several researchers in white coats are concentrating on various experiments. The test tubes and utensils in their hands shimmer with strange colors under the lamp, like a symphony of chemistry.
"I've discovered a new acaricidal compound!" A researcher named Jack suddenly exclaimed excitedly, "It has a good killing effect on the eggs and adults of many kinds of mites!" His colleagues gathered around to observe the results of his experiments.
"You calm down, we have to do a full safety evaluation test before we come up with a name for this new compound. An old researcher patted Jack on the shoulder.
After further verification, this new acaricidal compound does perform well, not only with high efficiency and low toxicity, but also with a wide control spectrum. To commemorate this important discovery, the research team decided to name it "bifenhydrazide".
In 2008, with the approval of China's Ministry of Agriculture, bifenazide was officially registered and began to be popularized. A number of preparation products such as suspension agent and water dispersible granules have also been launched.
An important new drug for the control of spider mites was born.
It can be seen that in the unremitting exploration of scientists, the bifenazide compound has been discovered, verified and put into practical application, so that agricultural production has obtained a new powerful weapon.
Its birth can be described as epoch-making significance.
The precise mechanism of action of bifenazide remains a mystery to this day. Scientists have put forward a number of hypotheses, but so far they have not been able to conclusively.
"It may exert a miteicidal effect by acting on the central nervous system of mites. Lead Researcher Smith said to several young researchers as he looked at the sample under the microscope.
Pointing to the nerve cells in the microscope, he explained, "Look, after adding the bifenazide extract to the sample, the synaptic conduction velocity of these nerves slowed down significantly.
"Ah, I see, it may inhibit neurotransmitter release or reception. A female doctor named Lydia nodded.
Other researchers have proposed another hypothesis, suggesting that it may work by inhibiting the oxidative phosphorylation pathway of the mite cytochrome chain, cutting the chain of energy metabolism.
However, these speculations need to be further demonstrated.
Although the mechanism of action of bifenazide is not clear, it can be confirmed that it can effectively control all life stages of mites, from eggs to adult mites can play a role in killing or inhibiting growth.
At the same time, bifenazine ester is also relatively safe for beneficial insects and plants. This is enough to prove that it is an excellent new acaricide.
"Bifenazine is like a mysterious killer, and we need to continue to decipher its 'killing methods' and catch its flaws. Lead Researcher Smith said half-jokingly.
He believes that one day scientists will lift the veil once and for all.
After the introduction of bifenazide ester, through extensive use, farmers and researchers further recognized and verified its excellent product characteristics.
"Dude, this biphenyl hydrazide is really powerful, all the red spiders in my vegetable field have been done!" Li Nong looked down and inspected the vegetable leaves, and said to Wang Nong next to him.
Wang Nong leaned over and took a look, only to see that there were no reptiles on the vegetable leaves, nodded and said, "Yes, and there is no residue, and the beneficial insects are not affected, and the effect of this medicine is really good."
In the laboratory of the local Academy of Agricultural Sciences, Xiao Gao, a staff member, is recording data on the number of mites collected from different plots. He found that the number of mites in the plots treated with bifenazide was consistently low, regardless of the temperature changes, while the control group fluctuated significantly.
"It turns out that bifenazide is really not sensitive to temperature, which shows that its stability in the field is very good. Xiao Gao compared the data and came to a conclusion.
Monitoring data also showed that bifenazide can be controlled for up to 20-25 days. This is undoubtedly good news for farmers during the busy farming season. And after testing, bifenhydrazine ester can control a wide range, not only for common spider mites, but also for some small lepidopteran pests.
"Bifenazide can be described as an all-rounder, the temperature is not afraid, the duration is long, the control range is wide, and it is very convenient for farmers to use. Xiao Gao is very satisfied with the conclusions of his research.
He believes that this acaricide will be welcomed by farmers because of its product characteristics.
As a new type of acaricide, there are many precautions for the use of bifenazide. Workers, peasants, and technicians have repeatedly stressed to farmers at meetings that only when they are used correctly can they exert their due acaricidal effect.
"When you use bifenazide, you must strictly follow the dosage recommended in the instructions. Counselor Zhang of the agricultural technology station used a laser pointer to circle the key points on the PPT, "Different crops and different pests are different, for example, the control of citrus red spider is 2,500 times the liquid, and the control of strawberry red spider needs to be increased to 4,000 times the liquid."
Several of the peasants present listened attentively, and some even took out small notebooks to take notes.
"In addition, we should also note that bifenazide ester cannot be mixed with organophosphorus and carbamate acaricides, which will reduce the efficacy of the drug or even lead to failure. Counselor Zhang continued to emphasize.
He hopes that through this exchange activity, farmers can improve their awareness of the correct and safe use of bifenazide, so as to play an important role in the prevention and control of red spiders and help the healthy development of agriculture.
After the meeting, the farmers also gathered around Counselor Zhang and asked a lot of questions. These ordinary people working in the fields, in order to fight against insect plagues for a bumper harvest, have also unconsciously accumulated a lot of valuable experience in prevention and control, which is also of great benefit to the research and development of pesticides.
Benzazide, the killer of red spiders, is still active in the front line of prevention and control more than 10 years after its inception. As other acaricides become more and more resistant, bifenazide, a new mode of action, becomes particularly valuable.
"According to the monitoring results, the spider mites have basically developed varying degrees of resistance to most old acaricides. At a meeting of pesticide research and development companies, researchers reported the latest data, "and due to the unique mechanism of action, there is no resistance to bifenazide."
This shows that it still has great market potential in the control of spider mites.
"That's right!" Dr. Liang, the moderator of the conference, nodded, "That's why we want to continue to develop new formulation products for bifenazide and expand its application range."
At the same time, it is also necessary to mobilize more scientific research forces to further understand its control mechanism, which is of great significance for the design of a new generation of acaricides.
It is foreseeable that the dazzling new star of bifenazide, his story and legend in the field of pesticide control, will continue to be written.