sgRNA Design and Activity Detection Virtual Simulation Software: Helping Every Nobel Prize in Medicine Dream At 5:30 p.m. Beijing time on October 7, 2024, the 2024 Nobel Prize in Physiology or Medicine was announced. Victor Ambros and Gary Ruvkun were awarded for their important contributions to the discovery of microRNAs and their role in post-transcriptional gene regulation. As an important part of biopharmaceuticals, genetic engineering has always played a pivotal role in the field of drug research and development. In order to help every Nobel Prize in medicine dream, OBIER has developed a series of medical and pharmaceutical virtual simulation software in medical education.
According to the characteristics of CRISPR/Cas9 gene editing technology, the virtual simulation software for sgRNA design and activity detection was established by using computer virtual reality technology, through 3D reconstruction and simulation experiments. Through this software, students can learn the technical principles and application scope of CRISPR/Cas9 gene editing technology, so as to master this cutting-edge molecular biology experimental technology. The establishment of this virtual simulation software greatly improves the effect of molecular biology experimental teaching, and increases the depth and frontier of experimental content. At the same time, students' comprehensive experimental ability, academic vision and scientific research interest have also been greatly improved.
3D reconstruction and simulation experiments
The virtual simulation software for sgRNA design and activity detection uses computer virtual reality technology to restore the real experimental scene and operation process through 3D reconstruction and simulation experiments. Students can visualize the key role of sgRNA in the CRISPR/Cas9 system and its dynamic changes in the gene editing process.
Experimental simulation and operation guidance
The sgRNA design and activity detection virtual simulation software provides experimental simulation functions for sgRNA design, and users can perform sgRNA design, synthesis, and activity detection operations in a virtual environment. The software is embedded with detailed step-by-step operation guidelines, students can follow the instructions, and the system will provide timely feedback and scoring according to the operation.
Personalized learning paths
The virtual simulation software for sgRNA design and activity detection has "reading and thinking" and "knowledge points" to provide a systematic explanation of relevant basic knowledge, in addition to "thinking questions", which can investigate the students' daily knowledge accumulation and the knowledge learned through the operation of the simulation software, and the system can automatically score the students' answers, so that students can fully realize the shortcomings of their own knowledge mastery, so as to further improve and improve.
As an efficient and convenient virtual simulation tool for genetic engineering, sgRNA design and activity detection virtual simulation software is of great significance for researchers and students to research and learn in the field of gene editing. We hope that with the assistance of a series of pharmaceutical virtual simulation products, more interdisciplinary high-quality talents can immerse themselves in experiments and innovations, impact more Nobel Prizes, and let the world see China's strength.