Author: Odd Boy
Editor: Li Xuewei
Typography: Li Xuewei
Outside! Outside! Here's a serious marriage notice:
"Peace" marriage
FALL
IN LOVE
"Peace" beautiful photo
Woman's name: Ping An
Date of Birth: December 24, 2020, Capricorn
Origin: United Kingdom
Birthplace: Qingdao Agricultural University
Current residence: Qingdao Agricultural University Yipin Villa
Occupation: Engaged in embryo engineering, somatic cell cloning and other scientific research work
Education: Requirements for the male at birth to receive higher education: English longhair cat, silver gradient. The pupil color is green, the pure London accent is preferred (there is no limit to the ownership of local dialects), and there is no disease and no moss.
Together, we can study topics related to the breeding of cloned cats, and we are welcome to contribute to science.
<h1 class="pgc-h-arrow-right" data-track="13" > the keyword "peace"</h1>
Born in an academic family, he now works in a public institution and is the first domestic college clone cat.
(High-quality female déjà vu in the cat world)
The main body was once thought to be an adult female forest cat that was a hybrid of a wild forest cat and a Chinese pastoral cat, but was actually an English longhair cat.
Although the social circle is limited and there are fewer opposite sexes around, it is not a house cat, but a sunny, cheerful, kind kitten, who is deeply liked by colleagues around and is a "group pet".
The family members are all scientific research workers, with a strong academic atmosphere, a superior family, and a villa.
(Welcome to the list)
Work conscientiously and responsibly, actively cooperate, and treat feelings seriously.
Today, "Ping'an" is 8 months old, equivalent to fifteen or sixteen years old for human beings, like a young girl of a wonderful age. And "Ping An" showed a performance of estrus last month, and its wedding date was also put on the agenda.
To assess whether the clone results of "Ping An" are good, reproductive ability is a very important indicator.
Its father, Dr. Zhao Minghui, said: "Everyone may think that 8 months of cats can not be counted as adults, why so early, mainly because this kind of cat has fewer people and is not easy to find." Blind dates may take a long time, so we prepare for it in advance, find them and let them mate when they are about 1 year old, and then the body is also a more suitable state. ”
<h1 class="pgc-h-arrow-right" data-track="75" > "ping'an" marriage tips</h1>
"Ping An", as a high-quality cat woman, also has strict requirements for kittens who come to "propose" and need to undergo two tests: interview and physical examination to enter the pending seat.
Perhaps the eager in-laws will ask, if the kitten is successful in blind date, after the cultivation is successful, the offspring will continue to engage in scientific research work?
Dr. Zhao Minghui, the father of "Ping An", said that after the "Ping An" safe and smooth childbirth, after the team judged the cat's reproductive ability, it would conduct non-injurious observations on the kittens and would not do some experiments. If the offspring of "Ping An" are normal, there is no plan to study kittens for the time being, and they will be given away as ordinary cats for adoption.
<h1 class="pgc-h-arrow-right" data-track="80" > excellent "ping an daddy" - Dr. Zhao Minghui and his team</h1>
Minghui Zhao, Ph.D. in Agronomy, is an associate professor at the College of Life Sciences, Qingdao Agricultural University. He mainly conducts research on the mechanism of somatic cell cloning and somatic reprogramming in animals.
The first elite working dog was independently cloned in 2016. Break through the 11-year technology monopoly of Huang Yuxi's team in this field. In 2017, an in vitro culture system for early embryos of canines was established. A total of 15 SCI-included papers have been published as the first author. Applied for 1 patent. He has also made speeches at international academic conferences many times.
Dr. Zhao Minghui introduced that they have been preparing for this project since 2019. At that time, he saw a suitable cat at the animal hospital, and after consultation with the cat owner, they took the skin the size of a fingernail on the cat. Cells are isolated from the skin for culture, and a large number of somatic cells are obtained after certain passages, which are frozen in liquid nitrogen tanks at minus 196 degrees Celsius.
After a period of preparation, the project began in July 2020, when the team matured the oocytes in vitro, removed the original nucleus during cloning, replaced it with the nucleus of the British long-haired cat, and artificially activated it and then conceived by the mother cat. Team members streamlined and improved somatic cell cloning methods, reducing the entire experimental process from the traditional 36 hours to 5 hours, which is a 7-fold reduction in time.
At the same time, the team adopted the operation mode of using only one culture medium in the whole process of the experiment, which avoided the embryonic damage that could be caused by frequent replacement of the culture solution, greatly reduced the operational risk, and improved the stability of the experiment. A total of 89 somatic cloned embryos were produced in this experiment and transferred to 7 surrogate mother cats, of which 3 were pregnant, and the pregnancy rate reached 43%, which was the world's leading level.
According to reports, most of the surrogate female cats are sent by someone or abandoned stray cats, after coming here, the scientific research team first checked and treated them, ate and drank well, lived well, raised a good body and learned to live in harmony with people, and the female cat with good physical performance in all aspects such as physical spirit is suitable for surrogacy.
On the afternoon of December 24, 2020, the kitten born on this day was named "Peace".
<h1 class="pgc-h-arrow-right" data-track="90" > some cold knowledge about cloning animals</h1>
So far, humans have successfully cloned animals: frogs, carp, sheep, rats, macaques, pigs, cows, cats, rabbits, deer, horses, dogs.
The most famous, of course, is the first cloned mammal born in 1996, the sheep Dolly. In 2003, Dolly died after being diagnosed with progressive lung disease.
On December 22, 2001, the first cloned cat, Copy Cat, was named "CC" thanks to pioneering cloning work by researchers at Texas A&M University's School of Veterinary and Biomedical Sciences (CVM). He died in College City on March 3, 2020, and CC died at the age of 18 after being diagnosed with kidney failure.
On August 20, 2019, China's first self-bred cloned cat "Garlic" was born. Its owner, Huang Yu, a Wenzhou boy, said that he originally had a cat named "Garlic" who died of illness after accompanying him for three years. Huang Yu spent 250,000 yuan to ask Beijing Sino Valley Biotechnology Co., Ltd. to perform the clone.
Figure | The left is the cloned cat "Garlic", and the right is the cloned cat (deceased)
Breakthroughs in cell cloning technology have had a positive impact in various research areas. Not only can it promote the development of animal disease models and drugs, but it also has a significant impact in the field of biomedical research, the pet industry and the protection of endangered species.
In addition, just like the owner of the cloned cat "garlic", the owner is willing to choose the cloning technology at a high price in order to "resurrect" his pet, which may also be a future trend. However, the cloned cat is still the original cat, and whether the commercialization of cloning technology will be abused and whether it is ethical is a widely discussed issue.
Of course, the most urgent thing is that we "safely" marry. At present, three cats have successfully broken through the siege and entered the final round. However, there is no best, only better! The marriage work did not stop at the time of publication, and "Ping An" was still waiting for the cat that belonged to it.
Let us wish "peace" an early harvest of Ruyi Langjun!
For reference:
http://smkxy.qau.edu.cn/content/fjs/97ba2d2ef852439ea49f42e0350e93fe
https://new.qq.com/omn/20210901/20210901A01D9Q00.html
https://news.sina.cn/2021-08-28/detail-iktzqtyt2734536.d.html?from=wap
https://www.thepaper.cn/newsDetail_forward_10801039