Another natural metabolic molecule in the human body has been found!
The Kennedy experimental team of Singapore's anti-aging national teacher published a paper in Aging: they found that the natural metabolite AKG, which intervened for 7 months, methylation age was 8 years younger.
Found from more than 40 molecules, 7 months younger than 8 years old?
The research team first identified more than 40 natural metabolites that may be associated with aging, and screened out AKG molecules through a series of studies: perhaps the most closely related to aging.
Start with animal experiments. The team selected 18-month-old animals (equivalent to 60-year-old humans), and after 30 days of AKG intervention, found that their survival time was extended by 5%-10%, and their health value was also increased by 50%, which meant that it played a role in healthy survival.
Overjoyed, the scientists listed AKG as a key research object and prepared to carry out further experiments. The research team invited 42 healthy elderly people with an average age of 63 years, with a male-to-female ratio of 2:1, to conduct a 7-month AKG intervention experiment.
(Illustration: Schematic diagram of the important physiological activities in which AKG participates)
It turned out that their physiological age was on average 8 years younger! The intervention was 7 months younger and 8 years younger, and such brilliant data surprised the first author of the paper, Professor Kennedy: many scholars have gradually joined the research and development of supplements, but I think AKG must have greater potential.
More power, the spring of natural metabolites is coming?
There are some substances in the human body that gradually decline with age and the metabolism of the body, and AKG is one of them. But its wonderful point is that through the complementary intervention of the acquired outside world, the human body functions are returned to a younger level. Such a substance has actually been discovered as early as 2013 - Coenzyme I.
The substance is an important pathway discovered by biologist Simcolet in the Harvard laboratory - the citric acid cycle, which provides the human body with more than 95% of energy. The experiment found that after 2 months of intervention, the survival time of 18-month-old animals was stretched by 22%, the indicators of athletic ability and muscle strength also tended to be younger, and the telomeres directly related to aging were also elongated.
Coenzyme I is also found in trace amounts in foods such as avocados, raw beef, and mushrooms, but because its content is too low, it cannot meet the needs of the body. However, after several years of research, mainland scientists have developed enzymatic technology to simplify the difficulty of purification. At present, the "Palovi pro" supplement has been landed, covering hundreds of thousands of groups after entering Jingdong, and the amount of outbound storage is as high as 100,000+.
Professor Xin Kelie also pulled his wife, father, and even the family dog to eat the molecule together, the 53-year-old claimed to be 21 years younger than the physiological age of the test, and the 80-year-old father even transformed into a climbing expert, and his physical strength was not inferior to that of young men. In recent years, Tsinghua University and the University of Tokyo have also carried out lin bed experiments one after another, which has proved its potential in intervening in the elderly. "Palo vervoy pro" supplements have frequently set off a craze in China, or they may also be related to this.
Interestingly, the discoverers of these two substances, Xin Kelie and Kennedy, are brothers in the same disciple, and there seems to be a sense of confrontation between Yu Liang in ancient times. But regardless of the substance, Professor Kennedy is convinced that natural metabolites will be the first truly intervention in old age.
(Photo: Photo by Kennedy and Xin Kelie)
Summary: Is the centenarian era really coming?
Technology is constantly advancing, so that human vision and average life expectancy are constantly being broadened. From 40 years old 50 years ago to nearly 80 years old now, things that were previously thought impossible are really happening quietly.
The hundred-year-old era seems to be really approaching us step by step. It's not just Professor Kennedy's confident "Palovi pro" supplement; Israeli scientists have also found the "O2ARK" hyperbaric oxygen chamber, which intervened for 3 months to return to 20 years old; American scientists have returned 114-year-old lymphoblasts to 0 years old through gene recomparation technology.
Analysts at Merrill Lynch have said that scientific and technological knowledge will increase at a rate of 1 times in 73 days, and a technological advance is sweeping in. The future of human health survival may be more than 100 years old...