For some families who have long suffered from infertility, being able to have a baby on their own is the most urgent hope, so when IVF technology appeared, they regarded this technology as the last hope for treating infertility. Although IVF technology has a good effect in the treatment of infertility, this technology cannot guarantee 100% success, because there are many factors affecting the success rate of IVF, and Hengjian Overseas will explain them one by one.
The following common factors affect the success rate of IVF are as follows:
Age factor:
Age is one of the important factors in the success rate of IVF assisted reproductive technologies. The study found that the success rate of test tubes between the ages of 25 and 34 was the highest, ≥ the success rate was reduced after the age of 35, and the success rate of > 40 years old was lower. With age, women's ovarian function is also decreasing, the worse the ovarian function, the fewer eggs obtained, the worse the quality of the eggs, the pregnancy rate decreases, and the miscarriage rate increases.
The quality of the embryo
The quality of the embryo is an important factor in the success rate of IVF, good embryos are easy to succeed, and bad embryos are not easy to succeed. Therefore, three good embryos have a pregnancy rate of 25% to 30%. Of course, implanting more embryos is easier to succeed, but it also increases the risk of multiple births, and good embryos come from good eggs, good sperm, and a stable laboratory culture system.
Uterine cavity factors:
The endometrium is the most important place for embryo implantation, just as fertile soil is needed for farming, and the appropriate endometrium is also needed for planting. When uterine abnormalities such as polyps, submucosal fibroids, uterine adhesions, endometritis and other lesions occur, they may cause the embryo to fail to implant, and eventually lead to the failure of the entire cycle.
Hydrosalpinx:
Hydrosalpinx is an important factor affecting the success rate of IVF assisted fertility technology, if not treated, the return to the uterine cavity, will "wash away", "drown" and "poison" the embryo, thereby greatly reducing the chance of embryo implantation. Studies have shown that the pregnancy rate of patients with hydrosalpinus is significantly lower than that of those without hydrophotomal, and the incidence of miscarriage and ectopic pregnancy will be greatly increased. In patients with hydrosalpinx, it is recommended to first treat the hydrops, ligate or remove the fallopian tubes, and remove the effects of the effusion on the bed.
Immune factors:
Studies suggest that the activity of systemic or local natural killer cells is abnormally elevated, which may have a toxic effect on embryos and hinder planting; Secondly, coagulation abnormalities such as "antiphospholipid syndrome" and "thrombophilia" lead to thrombosis in the small blood vessels of the placenta, resulting in insufficient blood supply to the endometrium, a decrease in the chance of embryo implantation or an increased risk of miscarriage.
Genetic factors:
In some couples with primary infertility or a history of adverse pregnancy, some couples have chromosomal abnormalities in their chromosomes. Therefore, preoperative chromosomal examination is very necessary.
Psychological factors:
Excessive psychological stress can lead to endocrine disorders and can also cause uterine muscle contractions. Studies have shown that IVF pregnancy rates are significantly lower in patients with excessive psychological stress compared to other patients.
Hengjian Overseas Reminder: Through the above introduction, I believe you should know that there are many factors that affect the success rate of IVF, so it is recommended that all patients should follow the doctor's advice to do a comprehensive physical examination before deciding to do IVF, actively prepare for pregnancy, relax their mentality, prepare in advance, and avoid adverse factors that affect the success rate of IVF.