In the cardiology ward, Mr. Li, a middle-aged patient with a haggard face, clutched a list of medicines in his hand, anxiously waiting for the director's ward rounds.
"Director, how should I be cured of my coronary heart disease? This eliminates heartache, heartache, and peace of mind, and the doctor prescribed me several medicines, and I was confused. As soon as Mr. Li saw the director, he couldn't wait to ask.
The director smiled slightly, motioned for Mr. Li to sit down first, and then turned to the young doctor behind him and said, "Xiao Zhang, you can explain to Mr. Li the difference and usage of these medicines." It's also an opportunity to learn, depending on how well you learn. ”
When Dr. Zhang heard this, his heart suddenly became nervous. He knew that the director was going to test him. However, he still mustered up the courage and began to answer for Mr. Li.
"Mr. Li, your coronary heart disease is a common cardiovascular disease. These three drugs are commonly used for the treatment of coronary heart disease, but their pharmacological effects, indications and contraindications are different. As he spoke, Dr. Zhang took out a small notebook from his pocket and prepared to explain it to Mr. Li in detail.
"First, let's take a look at the heartache. This is a nitrate drug whose main effect is to relax vascular smooth muscle and dilate peripheral arteries and veins, thereby reducing myocardial oxygen consumption, increasing coronary perfusion, and relieving angina. It's like loosening the ties to your heart and making it work easier. Dr. Zhang said figuratively.
"What about heartache?" Mr. Li couldn't wait to ask.
"Heartache, that is, nifedipine tablets, it is a calcium antagonist. You know, calcium is an important factor in the contraction of cardiomyocytes and smooth muscle cells. Heartache selectively inhibits the entry of calcium ions into these cells, thereby reducing myocardial contractility and reducing myocardial oxygen consumption. At the same time, it also dilates peripheral resistance blood vessels, lowers blood pressure, and reduces cardiac afterload. It's like giving your blood vessels and heart a break so they can get some rest. Dr. Zhang explained.
"Oh, I see. What about peace of mind? Mr. Li continued to ask.
"Propranolol, which is propranolol hydrochloride tablets, is a β blocker. This drug can block the β1 and β2 receptors on the heart, reduce the contractility and contraction speed of the heart, and inhibit the contraction of vascular smooth muscle and reduce the oxygen consumption of the myocardium. It's like putting a reducer in your heart to make it run more smoothly. Dr. Zhang patiently explained.
However, while Dr. Zhang was explaining, the director listened silently, nodding or shaking his head from time to time. After Dr. Zhang finished speaking, the director suddenly asked, "Xiao Zhang, what you said is very good. However, have you ever wondered why we are prescribing these three drugs to our patients? What are the connections and differences between them? ”
When Dr. Xiao Zhang heard this, he was stunned. He really didn't think about it. He only knew that these three drugs were used to treat coronary heart disease, but he really didn't know exactly why they were used together.
"Mr. Li, let me explain it to you." Seeing this, the director personally went into battle and answered for Mr. Li, "Although these three drugs are all used to treat coronary heart disease, their mechanisms of action and targets are different. Eliminate heartache mainly dilates blood vessels and increases coronary perfusion; Altitine mainly reduces myocardial contractility and reduces myocardial oxygen consumption; Propranolol mainly reduces the contraction rate and contractility of the heart, and inhibits the contraction of vascular smooth muscle. There are both complementarities and synergies between them. Like a well-planned campaign, each soldier has their own mission and role, and only when everyone works together can they achieve the final victory. ”
The director's words made Mr. Li and Dr. Xiao Zhang suddenly realize. It turns out that these three drugs are not prescribed casually, but carefully matched according to the patient's condition and needs.
"Are there any contraindications and precautions for these three drugs?" Mr. Li asked again.
"Absolutely." The director said solemnly, "Eliminating heartache is contraindicated for patients with acute circulatory failure and severe hypotension; Heartache is contraindicated in patients who are allergic to nifedipine; Propranolol is contraindicated for patients with bronchial asthma and cardiogenic shock. When using these medications, be sure to follow your doctor's instructions and do not increase or decrease the dose or stop taking the medication on your own. At the same time, it is also necessary to pay attention to the side effects and adverse reactions of the drug, and give feedback to the doctor in time. ”
Hearing this, the doubts in Mr. Li's heart were finally answered. He looked at the director and Dr. Xiao Zhang gratefully, and said, "Thank you, I finally understand now." In the future, I will definitely take my medication on time and have regular check-ups to try to recover as soon as possible. ”
The director and Dr. Xiao Zhang also looked at Mr. Li with a smile, and their hearts were full of relief and a sense of accomplishment. They knew that through this explanation and exchange, they not only helped Mr. Li solve his doubts, but also consolidated and improved their own medical knowledge.
This "knowledge contest" between patients, directors and doctors finally ended in a harmonious and happy ending. In this competition, it not only shows the breadth and profundity of medical knowledge, but also reflects the trust and understanding between doctors and patients.
(Note: This article is a fictional plot and aims to popularize scientific knowledge, and actual medical decisions should be based on the advice of professional doctors and the specific situation of the patient.) ）