From the subtle beauty of nature to the continuous improvement of human wisdom, the pursuit of beauty is the common aspiration of mankind. However, as our body's first line of defense, the skin often faces challenges such as skin inflammation and impaired barrier function of intense sun exposure, leading to skin problems such as melasma and pigmentation.
In this new era of technology-driven skin beauty, through in-depth research and repeated testing, Shiwanni ® has launched Shiwanni's ® "White Moonlight". Based on science, this product provides personalized solutions for beauty seekers, helping more beauty seekers relieve melasma and gradually restore their natural radiance and purity.
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Shiwanni's ® White Moonlight uses dual hot ingredients to start the journey of purity of the skin. The first is the "small extracellular vesicles" derived from umbilical cord mesenchymal stem cells, which are rich in bioactive substances such as anti-inflammatory factors, miRNA, proteins, etc. They penetrate deep into the skin, precisely inhibit the production of inflammatory factors, repair the damaged skin barrier[1], and inhibit the synthesis of melanin[2], reduce pigmentation, and improve melasma. In addition, "small extracellular vesicles" also have the ability to promote the health of capillaries in the dermis[3], repair the damage and loss of basement membrane, and sustain the continuation of skin health.
Another highlight is the addition of type III recombinant humanized collagen. As an important component of the extracellular matrix, type III recombinant humanized collagen can not only effectively enhance the skin barrier function [4], improve the skin's water retention ability, and make the skin more hydrated and plump[4]; It can also help improve inflammatory aging[4] and protect the skin from external factors such as ultraviolet rays. Its delicate texture melts effortlessly into the skin, regulating uneven skin tone and revealing a natural moonlit glow.
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Striving for excellence, Shiwanni ® has strict requirements for the quality of products. In the research and development process of the "White Moonlight" series, Shiwanni ® strictly follows international testing standards and high release specifications to ensure the quality and effect of the products. After purification, 98.7% of the "extracellular vesicles" were in the range of 30 - 150 nm, and the concentration was as high as 2X108 particles/ml, which ensured their high activity and high efficiency. At the same time, the "White Moonlight" series maintains a highly active state in a naturally grown liquid environment, providing a high-quality skin beauty experience for beauty seekers.
Shiwanni's ® "White Moonlight" is a ® testimony to the brand's unremitting pursuit of beauty. It is not only a medical beauty product, but also a manifestation of a life attitude - the pursuit of natural, healthy and flawless skin. In the future, we look forward to seeing more research on the application of extracellular small vesicles in the field of light medical aesthetics, and also look forward to more excellent light medical aesthetic products to help beauty seekers achieve flawless beauty of skin.
[1] Exosomes Derived from bone marrow mesenchymal stem cells as treatment for severe COVID-19, May 2020. Stem Cells and Development 29(12). DOI: 10.1089/scd 2020.0080
[2] Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis［J］.Cho et al. Stem Cell Research & Therapy (2018) 9:187
[3] Kim EH, Kim YC, Lee ES, et al. The vascular characteristics of melasma［J］. J Dermatol Sci, 2007,46（2）:111⁃116. doi: 10.1016/j.jdermsci.2007.01.009.
[4] Yu Wenyuan, Geng Dongyun, Zhuang Huiru, et al. Application effect of microneedle introduction of recombinant type III. humanized collagen in skin barrier function repair[J].Clinical Medical Research and Practice, 2024(007):009.)