11 drug regimens for the treatment of gout: inhibit uric acid production, promote uric acid excretion, improve redness, swelling, heat and pain, reduce urate crystals and tophi:
1. Febuxostat tablets + benzbromarone tablets
Febuxostat reduces uric acid production by inhibiting xanthine oxidase; Benbromarone promotes uric acid excretion by inhibiting the reabsorption of uric acid in the renal tubules. Combination of the two: from the production and excretion of two aspects of the joint effect to reduce the level of blood uric acid, improve the treatment effect. For patients who do not respond well to a single drug treatment, a combination of agents may provide better control of serum uric acid.
2. Colchicine tablets + etoricoxib tablets
Colchicine exerts anti-inflammatory and analgesic effects by inhibiting neutrophil chemotaxis, adhesion and phagocytosis. Etoricoxib is a non-steroidal anti-inflammatory drug that reduces inflammation and pain by inhibiting cyclooxygenase activity and reducing prostaglandin synthesis. During an acute attack of gout, a combination of them may provide rapid relief of pain and inflammation. Colchicine mainly plays a role in the pathogenesis of gout, while etoricoxib works in terms of reducing inflammation, and the two work together to better control symptoms.
3. Allopurinol tablets + probenecid tablets
Allopurinol reduces uric acid production by inhibiting xanthine oxidase; Probenecid lowers blood uric acid levels by increasing the excretion of uric acid in the kidneys. Intervening in uric acid metabolism from different pathways can be more effective in lowering serum uric acid. For patients with excessive uric acid production and poor excretion, the combination of drugs can take into account both production and excretion to improve the treatment effect.
4. Sodium bicarbonate tablets + diclofenac sodium enteric-coated capsules
Sodium bicarbonate can alkalize urine, making uric acid less likely to form crystals in the urine; Diclofenac sodium reduces prostaglandin synthesis by inhibiting cyclooxygenase activity, thereby reducing inflammation and pain. In the case of gout attacks, non-steroidal anti-inflammatory drugs such as diclofenac sodium are used to relieve pain and inflammation, and sodium bicarbonate alkalizing urine can help prevent the formation of uric acid crystals, reduce the risk of complications such as urinary stones, and also facilitate the excretion of uric acid.
5. Potassium citrate sustained-release tablets + ibuprofen sustained-release capsules
Potassium citrate can increase the concentration of citrate in the urine, inhibit the formation of calcium oxalate, calcium phosphate and other stones, and also help dissolve uric acid stones and prevent the formation of new stones; Ibuprofen extended-release capsules produce analgesic and anti-inflammatory effects by inhibiting cyclooxygenase and reducing the synthesis of prostaglandins. During a gout attack, ibuprofen extended-release capsules can provide quick relief from pain and inflammation. Potassium citrate can prevent the formation of uric acid stones, reduce the risk of complications such as urinary tract stones caused by gout, and also help maintain the normal pH of urine and promote the excretion of uric acid.
6. Losartan potassium tablets + allopurinol sustained-release capsules
Losartan lowers blood pressure while reducing blood pressure by promoting uric acid excretion; Allopurinol extended-release capsules reduce uric acid production by inhibiting xanthine oxidase. For patients with gout who have comorbid hypertension, losartan helps lower serum uric acid while controlling blood pressure. Combined with allopurinol sustained-release capsules, it can jointly regulate uric acid levels from both production and excretion, improve the therapeutic effect, and reduce the dosage of a single drug and possible side effects.
7. Gout Ding Capsule + Si Miao Pill
Goutding capsule has the effect of clearing away heat and dampness, invigorating blood circulation and fixing pain, and can play a role in promoting uric acid excretion and reducing inflammatory reactions. Si Miao Pill has the effect of clearing away heat and dampness, which can improve the symptoms caused by damp heat betting, and also help to reduce blood uric acid levels and relieve joint pain. The combination of the two can enhance the effect of clearing heat and dampness, clearing channels and relieving pain. It has a good relieving effect on joint pain, redness and swelling in gout patients, and at the same time promotes uric acid excretion from different angles, reduces blood uric acid level, and improves the overall efficacy of gout.
8. Compound tendon extension capsule + gout comfort capsule
Compound Stretch Muscle Capsule has the effect of clearing heat and dehumidifying, invigorating blood circulation, and can play an effective role by promoting blood circulation and reducing the deposition of uric acid in the joints. Goutshu Capsule has the effects of clearing heat, relieving dampness and detoxification, and can reduce blood uric acid levels and relieve symptoms by promoting uric acid excretion and inhibiting inflammatory reactions. Combined use can further enhance the effect of clearing heat and dampness, clearing channels and detoxifying. It has a good effect on relieving the symptoms of joint pain and swelling caused by gout, and at the same time, it works together from different aspects to improve the excretion ability of uric acid, reduce the level of blood uric acid, and provide more comprehensive treatment for gout patients.
9. Biqi capsule + Angelica pain pill
Biqi Capsule has the effects of nourishing qi and nourishing blood, dispelling wind and dampness, invigorating blood and relieving pain, and can play a role in improving the flow of qi and blood and relieving joint pain. Angelica Pain Pill has the effect of clearing heat and dampness, dispelling wind and relieving pain, reducing blood uric acid by clearing heat and dampness, dispelling wind and relieving pain and relieving joint symptoms. The combination of the two can have a synergistic effect on nourishing qi and blood, clearing away heat and dampness, dispelling wind and relieving pain. For patients with gout, it can not only improve the condition of insufficient qi and blood, but also effectively relieve the symptoms of joint pain, redness and swelling caused by dampness and heat, and improve the comprehensive treatment effect of gout.
10. Zhengqingfeng Ningning sustained-release tablets + Goutning granules
Zhengqingfeng Tingning Sustained-release Tablets have the functions of dispelling wind and dampness, invigorating blood circulation, diluting water and reducing swelling, and its active ingredients can inhibit the release of inflammatory mediators and reduce joint inflammation; Goutning Granules has the effect of clearing away heat and dampness, clearing channels and relieving pain, which can promote uric acid excretion and relieve pain. The combination can be used to treat gout from different angles. Zhengqingfeng Pain Ning Sustained-release Tablets focus on relieving joint inflammation and swelling, while GoutFeng Ning Granules focus on clearing heat and dampness and promoting uric acid excretion, which can improve the treatment effect of gout and reduce pain and discomfort for patients.
11. Kidney Pills + Tung Pills
It can promote the excretion of uric acid by regulating kidney function and enhancing the body's metabolic ability. It has the effect of dispelling rheumatism and relieving pain, and can relieve symptoms such as joint pain caused by gout. The combination of the two can synergize in tonifying the kidney, promoting yang, dispelling rheumatism and relieving pain. For patients with gout, on the one hand, the kidney function is improved to promote uric acid excretion through Yi Kidney Bi Pills, and on the other hand, the Fentong Pill relieves the symptoms of joint pain and improves the quality of life of patients. #寻找热爱表达的你#
