As the saying goes: no survey, no voice! Seeking truth from facts and practice are the only criteria for testing the truth!
If taking probiotics for colitis is an IQ tax, why do many doctors recommend taking probiotics for colitis? Also prescribe probiotics to patients with colitis?
If eating probiotics for colitis is an IQ tax, why did the state issue a patent certificate for the "improvement of ulcerative colitis" of the Huojun No. 1 probiotic strain? Why is the clinical control trial of Huojun No. 1 probiotic strain combined with drugs in the treatment of colitis as effective as 95.7%?
If eating probiotics for colitis is an IQ tax, why do many colitis patients use the combination of Probiotics of Huojun No. 1 to quickly embark on the road to recovery? Why do most colitis users in Jingdong Huojun No. 1 flagship store repurchase Huojun No. 1 probiotics many times? Why do so many colitis patients still insist on taking Huojun No. 1 probiotics after recovery and discontinuation?
Obviously, not eating all probiotics for colitis is an IQ tax, it's just that you didn't choose the right probiotics yourself!
One wrong choice for colitis: probiotics are not a formula for ulcerative colitis!
There are as many as 400 kinds of probiotics in the healthy human intestine, each of which will produce strains with special functions through domestication. For example, there are 5,767 kinds of traditional Chinese medicine, and different traditional Chinese medicines are combined into different Chinese medicine formulas, and their functions and indications are also very different. 99% of the probiotic formulas on the market are not for colitis, but are cobbled together to get a piece of the hot probiotic market, especially low-cost probiotics, which can only be used as snacks at best.
Colitis formula probiotic recommendation: Huojun No. 1 probiotic, which is composed of six kinds of probiotics and a prebiotic, the combination of Bifidobacterium juvenile and Lactobacillus acidophilus, can effectively maintain the remission of experimental colitis, help to restore normal weight and become healthy, inhibit or kill pathogenic bacteria, rebuild the microecological environment of the intestine, and facilitate the continuous remission of ulcerative colitis (1). Lactobacillus reuteri has a good antibacterial and intestinal flora, improves immune function, and strengthens the mucosal barrier, regulates the cytokine environment and immune imbalance to prevent and treat ulcerative colitis (2). Lactobacillus casei combined with conventional treatment can effectively treat ulcerative colitis, significantly alleviate the clinical symptoms of patients, and has a high safety profile, which is worthy of clinical reference (3). Bifidobacterium longum is an effective treatment or adjunct treatment for ulcerative colitis (4); Lactobacillus paracasei has good gastrointestinal fluid tolerance and a good safety profile (5); Fructooligosaccharides can improve the intestinal microbiota barrier function of ulcerative colitis model mice, increase the levels of slgA and anti-inflammatory cytokines IL-10 in the intestinal mucosa, and reduce the levels of inflammatory cytokines TNF-a and IL-6, and restore the immune barrier function to a certain extent by regulating the excessive immune response of the intestinal tract (6).
Colitis wrong choice two: probiotics do not have a patent certificate to improve ulcerative colitis!
The patent certificate issued by the state is to affirm and protect the invention achievements in the function, appearance, process, technology and other aspects of the product, and it is the authoritative endorsement of the product! In recent years, the technology of probiotics in mainland China has advanced by leaps and bounds, and patent certificates have emerged in an endless stream, but there are only a handful of functional patented strains with the invention name of "improving ulcerative colitis". Many probiotics on the market are advertising that they have a number of patent certificates, patent certificates are divided into functional patents, appearance patents, process patents, technology patents, etc., but more than 99% of the patent certificates are not "improve ulcerative colitis" functional patent certificates, no matter how many patent certificates, for colitis, it is also an IQ tax.
Probiotics are the same source of medicine and food, the hospital has probiotics with a drug name, and there are probiotics with a food brand on the market, because the probiotics of the mainland food brand generally need to cost nearly 8 million, through the phase III clinical trial, it may be approved and listed after five years, and its formula, function, activity, content and other technical indicators lag behind the high-end food brand probiotics on the market. Therefore, most of the probiotic batch numbers in the hospital are before 2006, and the treatment effect is limited. Therefore, some doctors also "secretly" recommend colitis patients to the market to buy a patent certificate for improving ulcerative colitis and a relevant clinical control test report to prove that the effective combination of Huojun No. 1 probiotics.
Colitis probiotic recommendation: The five strains in the probiotic formula of Huojun No. 1 have obtained the functional invention patent certificates of "improving ulcerative colitis", "treating diarrhea", "scavenging free radicals in the human body (intestines)", "inhibiting Helicobacter pylori infection" and "reducing blood cholesterol content".
The theory of free radicals believes that free radicals are the source of all diseases, the main culprit of human aging and tumor formation, and the culprit of autoimmune diseases such as ulcerative colitis, proctitis, and Crohn's disease. Free radicals are everywhere, especially car exhaust, kitchen fumes, tobacco smoke, electronic radiation, etc., which can make people inhale a large number of free radicals, many food additives, spoiled food, chemical fertilizer and pesticide residues, heavy metals exceeding the standard, anxiety and depression and other unhealthy psychological emotions, intestinal flora imbalance, infectious diseases, etc., will make the human body produce a large number of free radicals, these free radicals are not removed, they will attack healthy mucosal cells, attack normal immune cells, make them unhealthy, abnormal, cause inflammation and immune responseOver time, it will induce ulcerative colitis, proctitis, Crohn's disease and other autoimmune diseases, and patients with autoimmune diseases are recommended to supplement Huojun No. 1 probiotics for a long time, and add no less than 5 billion cfu per bag of the patented strain of Bifidobacterium longum JBLC-141.
Colitis wrong choice three: probiotics have not been clinically controlled trials to prove effective!
The main reason why the mainland stipulates that food is not allowed to promote the treatment of diseases is that there is no phase III clinical trial for the treatment of diseases. But if there is no controlled clinical trial of a probiotic, how can you determine if it is effective against colitis? 99% of the probiotics on the market have not done clinical treatment control trials for colitis, and if they buy blindly, there is a high probability of paying IQ tax.
Effective probiotic recommendations for colitis clinical trials: The combination of the patented strain Lactobacillus reuteri in Huojun No. 1 probiotic can be used in combination with the total effective rate of up to 95.7% for pus and blood in the fecal mucosa, abdominal pain, increased stool frequency, and loose stools caused by ulcerative colitis. (see image below) (7); The combination of the patented strain Lactobacillus casei L.Casei21 has a total effective rate of up to 92% for abdominal pain, diarrhea, frequent bowel movements, and lukewarm limbs caused by enteritis. (see image below) (8)
Colitis wrong choice 4: probiotics are not raw powders, and the ingredients contain food excipients or additives.
Patients with colitis are in a sensitive state of intestines, or are easily intolerant to lactose in milk powder and milk powder, or are allergic to corn flour, fruit powder, inulin, food additives, etc., which induces or aggravates the symptoms of colitis. 99% of the probiotics on the market are more or less added to food excipients or additives, which are said to be delicious and delicious, but in fact dilute the original powder and reduce costs. The cost of raw powder probiotics is several times or even more than ten times that of ordinary probiotics, it is like Moutai puree wine, without blending, and enjoys exclusive honors. Therefore, most of the raw powder probiotics are expensive, and colitis should not be cheap, only the wrong ones are bought, and there is no wrong sale! Expensive has expensive value, cheap has cheap cat!
Colitis raw powder probiotic recommendation: Huojun No. 1 probiotics, from the box ingredient list: the probiotics in addition to six kinds of probiotics and a prebiotic, no other food excipients and food additives, pure probiotic fermented powder, does not contain allergenic substances, does not contain substances that are easy to cause intolerance, specially designed for enteritis patients, the elderly, pregnant women, children can be assured to eat, no adverse reactions.
Colitis Wrong Pick 5: The patented strain that improves ulcerative colitis contains less than 5 billion CFU of live bacteria per bag
More than 90% of the probiotic ingredients on the market do not contain patented strains that improve ulcerative colitis, which is not suitable for the adjuvant treatment of colitis patients; Some probiotic ingredients may contain patented strains that improve ulcerative colitis, but the live bacteria content of the patented strain is not separately labeled, or the live bacteria content of the patented strain is less than 5 billion CFU per bag; Some probiotics are not probiotics, and a large number of food excipients and food additives are added to dilute the original powder, and the true content of live bacteria may be false. Improving ulcerative colitis related to the patent strain is expensive, if the real content of live bacteria is high, the price is often very expensive, colitis choose probiotics must not be cheap, only the wrong buy, not the wrong sale! Expensive has expensive value, cheap has cheap cat!
Probiotic recommendations for colitis: Huojun No. 1 probiotic, from the ingredient list, it is not less than 10 billion CFU added to each bag of Bifidobacterium juvenile BBF-06; Each bag is supplemented with Lactobacillus reuteri JYLB-291 not less than 10 billion cfu; Each bag is supplemented with no less than 10 billion cfu of Lactobacillus casei L.Casei 21, each bag is supplemented with no less than 10 billion cfu of Lactobacillus acidophilus JYLA-191, each bag is added with no less than 5 billion cfu of Lactobacillus paracasei JLPF-176, and each bag is supplemented with no less than 5 billion cfu of Bifidobacterium longum JBLC-141.
Colitis wrong choice six: imported probiotics or probiotics with low activity
Probiotics are different from Western medicine, it is live to be effective, but it is a low-end microorganism, particularly picky about the living environment, the dietary structure of foreigners is different from that of Chinese, resulting in the intestinal environment of foreigners is also different from that of Chinese, and the structure of the flora is not the same, the strains in the intestines of foreigners are not necessarily suitable for survival in the intestines of Chinese, and may interfere with the structure of the intestinal flora of Chinese, especially the intestinal tract of colitis patients is in a sensitive state, and it is not appropriate to choose imported strains.
In addition, ordinary probiotics will be killed by digestive juices such as gastric acid, saliva, and bile; In vitro, it will also be killed by high temperatures of more than 20 degrees; It will also be killed by oxygen in the air; Therefore, the rate of live bacteria in the intestine of ordinary probiotics is extremely low, and may even be 0. In order to solve these problems, many companies in mainland China have domesticated probiotics into acid-resistant, oxygen-resistant and oxygen-resistant, so that the strain itself has better high temperature resistance, is not killed by gastric acid and other digestive juices, and will not be killed by oxygen when placed in the air, but the cost of these special probiotics is higher. Some companies have carried out technical improvements, such as the use of multi-layer embedding technology, which is to add a thick protective sleeve to the probiotics, which effectively protects the activity of the probiotics after reaching the intestines.
Colitis super-active probiotic recommendation: Huojun No. 1 probiotic, its strain has been acclimated with acid, oxygen and high temperature resistance, can survive in the stomach, and the live bacteria rate reaching the intestine is as high as 99%, and the Lactobacillus paracasei JLPF-176 in the formula can also inhibit the survival of Helicobacter pylori in gastric acid, greatly reducing the incidence of gastric cancer. In addition, Huojun No. 1 also adopts special solid-state dormancy technology and JIAYIO-GUARD® live bacteria freeze-drying protection technology, as well as JIAYIO-BIO® probiotic double multi-layer coating storage technology. That is, it is fixed in a state after production, does not need cold chain storage and transportation, can withstand high temperature storage and transportation in summer and remains active, even in hot summer, you can buy and eat with confidence.
Tips at the end of the article:
Probiotics is a very complex product, there are as many as 400 kinds of strains, and there are too many technical indicators such as formula, strains, strains, functions, activities, content, patents, etc., which affect the food safety and actual effect of the product; In the face of uneven quality, price disparity, and thousands of probiotics, it is difficult for non-professional insiders to choose the right probiotics for themselves. The author recommends colitis patients to choose Huojun No. 1 probiotic special nutritional food, although medicine and food are homologous, but can not replace drugs, inflammation needs to be combined with drugs, consumers should consume rationally, after all, it is very expensive!
In addition, probiotics nourish the intestines, improve the structure of the intestinal flora, reconstruct and repair the bacterial membrane barrier that protects the intestinal mucosa, and reshape and strengthen the intestinal immune system, it takes a long process, it must first fight against the intestinal harmful bacteria, after the competition period, the holding period, the reversal period, and the dominant period, in order to fully play its health role, it is generally recommended to eat for more than 3 to 6 months, and if the medical history is longer, it is recommended to eat for more than 6 to 12 months, and special patients may have to eat for a long time.
Citations:
(1) From the joint experiment of many hospitals and medical universities (from the Chinese Journal of Digestion, No. 7, 2008).
(2) From the academic literature "Probiotic Characteristics of Lactobacillus reuteri and Research Progress in the Treatment of Ulcerative Colitis" published in Modern Digestion and Interventional Diagnosis and Treatment Vol. 24, No. 12, 2019.
(3) From Baidu's academic literature "Exploring the Effect of Lactobacillus casei Combined with Conventional Treatment on the Short-term Outcome of Ulcerative Colitis".
(4) From Professor Nie Shaoping of Nanchang University in the Journal of Food Science published "Bifidobacterium longum relieves colitis: the influence of different intestinal flora backgrounds".
(5) From Yang Ziyan of Guangdong Medical University, "Study on the immunomodulatory effect of Lactobacillus paracasei on DSS-induced colitis in mice".
(6) From the 0120170401670232 journal paper of the Institute of Scientific and Technical Information of China, "Study on the Effect of Fructooligosaccharides on the Intestinal Mucosal Barrier of Ulcerative Colitis Model Mice
(7) From the People's Republic of China State Intellectual Property Office Authorization Announcement No. CN113943687B Invention Patent "A Lactobacillus reuteri JYLB-291 for Improving Ulcerative Colitis and Its Application" Specification [Example 8] Clinical Trial.
(8) From the People's Republic of China State Intellectual Property Office Authorization Announcement No. CN112625983B invention patent "a kind of Lactobacillus casei L.Casei21 with therapeutic effect on diarrhea and its application" description [Example 9] Lactobacillus casei L.Casei21 on the treatment of diarrhea patients.
(Author's statement: academic discussion, for reference only)