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Written by | Song grammar
Diabetes is a chronic disease that affects more than 540 million people worldwide. With changes in lifestyle and eating habits, diabetes has become the third most important factor affecting human health. In China, there are more than 114 million adults living with diabetes, accounting for a quarter of the world's diabetic patients, the highest number in the world, and this number continues to rise.
Diet plays a vital role in the development of diabetes. Although there are many studies evaluating the role of low-carb diets in type 2 diabetes, most studies have focused on the management and mitigation of diabetes. However, the long-term effects of low-carbohydrate diets on the risk of developing diabetes are unclear.
近日，澳大利亚莫纳什大学的研究人员在" Diabetes & Metabolic Syndrome：Clinical Research & Reviews "期刊上发表了一篇题为" Association of low carbohydrate diet score with the risk of type 2 diabetes in an Australian population：A longitudinal study "的研究论文。
This large-scale study showed that a low-carbohydrate diet was associated with an increased risk of diabetes, with 38% of people with carbohydrate energy having a 20% increased risk of diabetes compared to those who provided 55% of their carbohydrate energy.
Mediator analysis showed that this was largely caused by obesity, with BMI mediating 76% of the association.
In the study, researchers analysed data from 39,185 participants in the Melbourne Collaborative Cohort Study (MCCS) to assess dietary patterns through the Low Carb Diet Score (LCD), analysing the association between low carbohydrate diet scores and the incidence of type 2 diabetes.
Low-carbohydrate diet score: Scored based on energy intake based on fat (0-10), protein (0-10) and carbohydrate (10-0), with a score ranging from 0-30, with higher scores indicating more fat and protein energy intake and lower carbohydrate energy intake.
A total of 1,989 new cases of diabetes were recorded during the 17-year study.
Low-carbohydrate diet score grouping
It was found that higher LCD scores were associated with an increased risk of type 2 diabetes, suggesting that a low-carbohydrate diet pattern may increase the risk of diabetes.
Those with the highest LCD scores (38% for carbohydrates) had a 20% increased risk of diabetes compared to those with the lowest LCD scores (55% for carbohydrate energy).
The analysis found that this is largely caused by obesity, with BMI mediating the association of 76% of low-carb diets with diabetes.
Studies have shown that a high LCD score diet (a low-carb diet) contains relatively more fat, protein than a low LCD score diet, so the positive correlation with diabetes may be due to the high fat content, which increases the risk of obesity, which is an important risk factor for diabetes.
In conclusion, this 17-year prospective longitudinal study showed that lower carbohydrate dietary patterns were associated with an increased risk of type 2 diabetes, with BMI mediating the association between a low-carbohydrate diet and diabetes in 76%.
Not only that, but a low-carb diet is not good for longevity!
2023年9月，中南大学的研究人员在" Nutrients "期刊上发表了一篇题为" Inverse J-Shaped Relationship of Dietary Carbohydrate Intake with Serum Klotho in NHANES 2007–2016"的研究论文。
Studies have shown that carbohydrate intake affects serum Klotho levels, which are highest when carbohydrate intake accounts for 53.7% of total energy intake.
Klotho is a longevity factor that declines with age, and its expression levels are closely related to aging. This means that a low-carb diet may not be conducive to longevity, and when carbohydrate energy intake accounts for 53.7% of total energy intake, it is most beneficial for longevity.
Bibliography:
https://doi.org/10.1016/j.dsx.2024.103049
https://doi.org/10.3390/nu15183956
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