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Frontiers of Neuroscience: Research Hotspots of Spinal Cord Stimulation

引言(来源于ChatGPT)

Spinal cord stimulation is a well-established neuromodulation technique used to treat patients with chronic pain and certain spinal cord injuries. The following are the research hotspots and future development directions of spinal cord electrical stimulation:

1. Chronic pain management: Spinal cord stimulation is widely used to treat chronic pain, such as lumbar postoperative pain syndrome, complex regional pain syndrome, postherpetic neuralgia, etc. Researchers are exploring new applications of electrical spinal cord stimulation in the treatment of various neuropathic pains.

2. Rehabilitation after spinal cord injury: Electrical spinal cord stimulation has shown potential in rehabilitation after spinal cord injury, through which neuromuscular activity can be activated and motor function can be restored. A research team at Fudan University has developed a new generation of cerebrospinal interface devices that are expected to help paralyzed patients walk again.

3. Technological advances: Researchers are developing more advanced spinal cord stimulation techniques, such as dorsal root ganglionic stimulation, which can stimulate nerves more precisely and reduce abnormal sensations in non-painful areas.

4. Closed-loop spinal cord stimulation system: The closed-loop spinal cord stimulation system can automatically monitor the patient's body's response to stimulation and adjust the intensity of electrical stimulation in time to provide a more personalized treatment plan.

5. Waveform innovation: Spinal cord stimulation waveform research is developing rapidly, especially high-frequency spinal cord stimulation, which provides analgesic effects through high-frequency electrical pulses without the abnormal sensation that traditional spinal cord stimulation may bring.

6. Electrode materials and designs: Researchers are exploring new electrode materials and designs to improve the effectiveness of spinal cord stimulation and patient comfort. For example, through highly integrated packaging technology and high-efficiency conversion technology, the size of the device is reduced and the efficiency is improved.

7. Clinical trials: Clinical trials of spinal cord stimulation have become a research hotspot, promoting the transformation of basic research into clinical applications, especially in the field of chronic neuropathic pain.

8. Remote program control technology: With the development of remote program control technology, the program control after spinal cord stimulation may be remotely used in the future to improve the accessibility and convenience of treatment.

9. Cost-effectiveness and complication studies: Investigators are evaluating the cost-effectiveness ratio and potential complications of spinal cord stimulation therapy to optimize treatment options and improve the safety of treatment.

10. Mechanism research on spinal cord stimulation: in-depth exploration of the neurobiological mechanism of spinal cord stimulation and analgesia to provide a theoretical basis for clinical application.

In summary, the research hotspots and future development directions of spinal cord electrical stimulation focus on improving treatment efficacy, optimizing technology, expanding the scope of application, and enhancing patient experience. With the continuous advancement of technology and the deepening of clinical research, spinal cord electrical stimulation is expected to provide effective treatment options for more patients.

Big data analytics

检索数据库:Medline

检索工具:文献鸟/PubMed

Search time: 2024-10-10

检索词:spinal cord stimulation

1. Overview of the paper

In recent years, 27,666 articles have been published internationally on spinal cord electrical stimulation included in Medline, including 103 in 2019, 739 in 2020, 827 in 2021, 773 in 2022, 822 in 2023, and 726 in 2024. Conduct big data analysis of its latest 3991 articles, and use ChatGPT to further understand the research hotspots of spinal cord stimulation.

Frontiers of Neuroscience: Research Hotspots of Spinal Cord Stimulation

2. Institutions active in the field of spinal cord electrical stimulation research

Frontiers of Neuroscience: Research Hotspots of Spinal Cord Stimulation

United States Harvard Medical School published 38 papers, United States University of Pittsburgh published 29 papers, United States University of Louisville published 26 papers, United States Case Western Reserve University published 26 papers, and United Kingdom Brunel University published 26 papers.

Frontiers of Neuroscience: Research Hotspots of Spinal Cord Stimulation

Hospitals with active publications in the field of spinal cord stimulation research: Mayo Clinic in United States published 69 articles, Balgrist University Hospital in Switzerland (21 articles), Cleveland Clinic in United States (18 articles), University of Kansas Medical Center in United States (17 articles), Beth Israel Deaconess Medical Center in United States (16 articles), Massachusetts General Hospital in United States (16 articles).

3. Journals with a large number of authors in the field of spinal cord stimulation research

Frontiers of Neuroscience: Research Hotspots of Spinal Cord Stimulation

从发文来看,发表脊髓电刺激研究文章数量较多的期刊有Neuromodulation (IF=3.2)、Pain Pract (IF=2.5)、Front Neurosci (IF=3.2)、J Clin Med (IF=3)、J Pain Res (IF=2.5)、Sci Rep (IF=3.8)、World Neurosurg (IF=1.9) 等。

4. Academics and their networks active in the field of spinal cord stimulation

Frontiers of Neuroscience: Research Hotspots of Spinal Cord Stimulation

International experts active in the field of spinal cord electrical stimulation research: Gulati, Sasha, St. Olaf Hospital, Norway; Squair, Jordan W, University of Lausanne, Switzerland; Mekhail, Nagy, Cleveland Clinic, United States; Capogrosso, Marco, University of Pittsburgh, United States; Hara, Sozaburo and others from Norway University of Science and Technology are active in this research field. There are many more excellent researchers, and it is impossible to list them all due to space limitations.

Limitations of this data analysis:

A. This report is a visual report based on the PubMed database based on the PubMed database, based on the search results of the set search terms, within a limited time and number of documents.

B. The purpose of the big data analysis of the "Literaturebird" analysis tool is to present an overview of recent research in the field and is for academic communication purposes only; There is no ranking significance.

C. The statistical ranking of the results of the "Literature Bird" analysis tool on the active unit, author, etc., and only the number of papers in the unit where the first author's paper is located is counted; That is, after the paper is retrieved and downloaded, only the first author's unit is retained for each paper, and then the number of papers in each unit is counted. When there are different spellings of the same unit, PubMed treats it as two different units. In the same authorship arrangement, only the number of papers published by the first author and the last author is counted. If the author's name has a different spelling, it will be processed by the PubMed search platform according to the different authors.

D. The conclusion of this paper is completely derived from the "Literature Bird" analysis tool, due to the limitations of search terms, the scope of literature included in the search database and the search time, it does not represent the views of this journal, and the data content is likely to be inaccurate.