One bucket poor, two bucket rich, three buckets and four buckets sell tofu, five buckets and six buckets open a pawnshop..., this familiar nursery rhyme, I don't know where you are, how to sing it?
I believe that when we were young, our parents or elders at home all picked up our fingers and counted for us how many "buckets" and several "dustpans" there were in the 10 fingers, and when we grew up, we all understood that everyone has different fingerprints, and these different fingerprints, as the nursery rhymes sing, can determine whether we are rich or not, whether we are healthy and long-lived?
Many people may hear this and say, isn't this all about coaxing children to play, how can there be a scientific basis? However, in recent years, the relevant research carried out by Chinese scientists has gradually revealed that there may indeed be a certain correlation between fingerprints and life and health, and this study was published in the first issue of Cell magazine in 2022.
Everyone's fingerprints are different, which has also become an important sign of personal identity, as early as 1864, should the plant morphologist Gru published a paper on fingerprint recognition technology, some people once believed that fingerprint recognition was first discovered by Europeans, but if you look at the Chinese classics, you will find that our intelligent Chinese ancients, as early as 3000 years ago, have begun to use fingerprint technology. According to the Zhou Li, "The lawsuit is stopped by the conclusion of the letter with a quality agent." The "quality agent" in the text refers to the documents of the buyer and the seller, and after pressing the handprint, it proves that they all agree with each other, and avoids disputes and litigation.
Fingerprint is an important feature information to identify a person, so that in forensic science, civil, contract signing and other aspects have been used so far, research data show that the probability of appearing two exactly the same fingerprint is one in fifteen billion, that is, the probability of two people's fingerprints relative is minimal.
Folk fingerprints also have a variety of sayings, and the simple distinction between "bucket" and "dustpan" is the most popular one, bucket usually refers to the fingerprint nature of the finger can form a regular circular fingerprint around the finger, shaped like a container for storing grain "bucket", so it is called "bucket" in many places, and some places are called "Luo", while the other fingerprint is relatively loose, resembling the "dustpan" at home.
There are also many folk sayings about fingerprint buckets and dustpans, for example, we said at the beginning that one is poor, two buckets are rich, etc., which means that the more buckets, the more grain can be saved, the richer they will be, so there are also "ten-finger dustpans have no buckets, only no place to pack them outside", but there are also places where there is such a saying: "Ten dustpans have no buckets, and the dustpans are not worried." It means that even if there is no "fight", you can live a carefree life.
Some such statements, of course, do not have any scientific basis, just a beautiful meaning of the folk or a nursery rhyme, but as a unique fingerprint of everyone, the physiological mystery is also a lot of curious aspects, and the related scientific research is not rare, but most scientific research does not analyze the relationship between different fingerprints and physiology and health from the perspective of big data? The latest research results of the Chinese Academy of Sciences may subvert the traditional cognition of many people.
The study was conducted by more than a dozen scientific research institutions inside and outside the United Nations, such as the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences and the team of academician Jinli of Fudan University, on the relationship between the formation of finger pattern phenotype and the gene related to limb development, and the study is expected to provide a certain scientific basis for the early identification and screening of specific diseases through fingerprint phenotype.
The fingerprint of the human body begins to develop in the fetal development stage, in the 10th week of the embryo, the fingertip part begins to develop a spherical bulge, and in the fourth month of pregnancy, the fingerprint has been formed on the skin of the fetus, and this fingerprint feature almost no longer changes, many friends may think that the fingerprint is located on the skin of the finger, so it may be associated with the relevant genes of the human body to develop and form the skin, but the analysis of this new study found that the main genes that determine the fingerprint, the main genes that affect the fingerprint, There is a strong association with genes that affect limb development, rather than pathways related to skin development. That is to say: fingerprint-related genes affect the formation of the final fingerprint pattern by regulating limb development.
After genome-wide association scans and multi-population meta-analyses for more than 23,000 individuals, the researchers identified 43 genetic loci associated with human fingerprint patterns. In the study, we also found some interesting phenomena related to fingerprints and limb development, you may wish to self-control:
There is a close relationship between the finger pattern and the proportion of finger length, for example, the more people who "fight" with both hands, the longer the little finger tends to be, and the shorter the length of the entire palm.
The fewer "buckets", the longer the distal joints of the index finger (knuckles near the fingerprint formation).
The greater significance of this study lies in the in-depth study of fingerprint phenotype, understanding the strongly related genes formed by fingerprints, so as to predict the role of human health, diseases and other aspects through these genes, such as genes responsible for limb development, which are not only related to limb development, but also may play a role in other aspects of "one cause and many effects". At present, the research team is cooperating with the Children's Hospital of Fudan University and other units, hoping that the relevant research results can be applied to the early screening of newborn congenital diseases as soon as possible to achieve earlier diagnosis and treatment.
In fact, fingerprint research is only one aspect of the "human phenotype group" research, in recent years, in the field of life sciences, phenotype research has become another focus after both genetic research, the so-called phenotype refers to the various biological characteristics of life, in addition to fingerprints, people are single eyelids or double eyelids, skin color depth or light, ear shape, speed, strength, etc., are the phenotypic indicators of the human body, compared to genetic research, phenotype group research is more for and cross-scale biological indication research, Through the precise measurement of the human phenotypic group system, massive biological information data can be accumulated, so as to discover the correlation mechanism between gene-phenotype-environment, and finally applied to accurate diagnosis, intervention, regulation, treatment and other aspects, which is of great significance to human health.
We Chinese scientists have long recognized the importance of phenotypic group research, in 2015, set up a major project, and in 2019 in Shanghai Zhangjiang established the world's first cross-scale multi-dimensional human phenotype group precision measurement platform, at present, more than 800 Shanghai 20 to 60 years old or volunteers have completed the panoramic epigraphy of more than 30,000 indicators per person on the platform, the world's first "human phenotype group navigation map" has also been preliminarily drawn, Among them, 1.5 million strong associations were found, of which nearly 40% were cross-disciplinary strong associations, many of which were the first discoveries in the scientific community.
I hope that our scientists can continue to move forward and further expand the relevant research, and I believe that in the near future, this related research will be gradually applied to the fields of disease screening, diagnosis, and drug development, and further escort our health.