There are often bao mama messages to consult the bacteria about folic acid:
Should I take folic acid during pregnancy?
When should I start supplementing with folic acid?
Will there be any serious consequences of not eating on time during pregnancy?
Today, let me show you a recent case.
The balls of meat at the caudal end of the baby's spine are very eye-catching.
The condition is scientifically called dominant spina bifida meningocele, which is a type of NTDs.
NTDs, also known as neural tube malformations, are a group of defects caused by incomplete neural tube closure in embryos during development, including anencephalic children, bulging brains, spina bifida, etc., which is one of the most common neonatal defect diseases.
Its formation mechanism is very complex, and it is the result of a combination of genetic and environmental factors.
Studies have found that more than 50% of cases of neural tube defects (NTDs) in newborns are associated with folate deficiencies in the first trimester of pregnancy.
At present, there are also many studies and findings that folic acid supplementation has an important preventive effect on the occurrence of NTDs, which can prevent the occurrence of NTDs in 50% to 70%.
Many people may also wonder, then many foods have folic acid, why does this still occur?
In fact
It is not enough to supplement "folic acid" with food alone
Folic acid is a B vitamin that dissolves in heat and cannot be synthesized by the body itself.
Although the foods we usually eat are also rich in folic acid, such as quinoa, dried soybeans or miscellaneous beans, curd bamboo, spinach, fennel, amaranth, animal liver, lean meat, duck eggs and so on.
However, due to the unstable structure of folic acid, it is easy to be destroyed in the cooking process of food, and it is also affected by a variety of factors in the process of human absorption, and the absorption and utilization of the human body is limited.
So we often don't get enough folic acid from our daily diet.
Moreover, the bioavailability of natural folic acid is low, only about 60% of synthetic folic acid.
Some people have calculated that if the human body wants to consume 0.4mg of folic acid (the amount of 1 supplement), it needs to eat 44 medium-sized tomatoes, or 17 cups of orange juice, or 200 medium-sized red apples.
Therefore, we simply cannot meet the dose of folic acid needed to prevent neural tube defects by changing the diet!
If the required folic acid is not enough during pregnancy, it may also lead to many serious consequences.
●Increased fetal treasure risk:
Increased risk of neural tube malformations: eg, spina bifida, anencephaly, and bulging brain
Cleft lip and palate, gastrointestinal tract, kidney and other organ malformations
●Increased risk of pregnant mothers:
Megaloblastic anemia
Premature birth, miscarriage, stillbirth
Risks such as preeclampsia increase
Folic acid must be so supplemented!
■ time — dosage
According to the 2020 edition of the consensus of multidisciplinary experts on clinical rational supplementation of folic acid in China:
People without risk factors:
Folic acid supplementation begins at least 3 months before pregnancy
Daily supplementation is 0.4 mg or 0.8 mg until the end of 3 months of pregnancy.
Have a history of NTDs or have a spouse with NTDs:
Starting from a possible pregnancy or at least 1 month before pregnancy, supplement 4 mg or 5 mg of folic acid daily until the end of 3 months of pregnancy.
(At present, there is no 4 mg supplement production in China, so 5 mg is recommended)
Those with diabetes, obesity, epilepsy, malabsorption of the gastrointestinal tract, or taking medications that increase the risk of developing fetal NTDs:
Such as carbamazepine, valproic acid, phenytoin, primidone, phenobarbital, metformin, methotrexate, sulfasalazine, trimethoprim, triamterene, trimethoprim, cholestyramine and the like
Folic acid supplementation of 0.8 to 1.0 mg/day is recommended from the possible pregnancy or at least 3 months before pregnancy until the end of 3 months of pregnancy.
MTHFR 677 TT Genotype women:
Depending on individual circumstances, the amount of supplementation may be increased or the preconception period may be extended.
■ Whether men also need to eat folic acid when trying to conceive
At present, there is no clear study to determine the specific dosage of folic acid supplementation for men, and it is possible to increase dietary supplements or take additional supplements.
How to choose folic acid?
Don't spend money for free!
Since 2009, the state has issued a document, first distributing this 400 micrograms of folic acid that has been proven effective in rural areas free of charge, and now it has developed to free distribution in both urban and rural areas.
Target population: women who are pregnant and women who are pregnant within three months of pregnancy
Collection Process:
Perinatal women can use their identification certificate or maternity service card to collect folic acid directly from the community health service where they live.
Normal pregnant women are issued according to the dose of 0.4 mg folic acid per person per day after signing the informed consent form, and the dose is issued for 6 months at a time, and the relevant registration is carried out.
The state distributes, free and safe, and the dosage can completely achieve the preventive effect!
Many people may have such questions:
"Why is the quality of folic acid of drugs so high, compared to the price of folic acid of health products is so low?" Cheap is not good, right? ”
The price of medicines is controlled by the State and is a necessity, especially for such drugs, which can effectively prevent birth defects.
Health care products are purely personal preference consumption, only a choice, and are not subject to strict price control.
And the restrictions of health care product advertising are much looser than drugs, health care products will spend a lot of investment in advertising promotion, and there are first-level agent commissions, and the sharing of these costs naturally falls on consumers.
Therefore, if there are ingredients in health care products and drugs, the preferred drugs will be more secure and cost-effective.
Secondly, choose different types according to their own situation:
●A balanced daily diet is recommended: "folic acid tablets alone"
This common drug (OTC) folic acid tablets, folic acid 400 micrograms, unit price of 0.26 yuan / tablet, to reach the minimum supplement of 400 micrograms need 1 tablet, a day cost of 0.26 yuan.
●Recommended choice for an unbalanced daily diet: "Multivitamin with Folic Acid"
Among them, the folic acid content is the focus of the purchase!
This multivitamin mineral tablet, folic acid 175.63 micrograms, unit price 1.77 yuan / tablet, to reach the minimum supplement of 400 micrograms need 3 tablets, a day cost of 5.31 yuan.
This ferrous folate, folic acid 217 micrograms, unit price of 1.98 yuan / piece, to reach the minimum supplement of 400 micrograms need 2 tablets, a day cost of 3.96 yuan.
From the perspective of cost performance and health needs, bacteria do not recommend that everyone blindly pursue high-priced health care products, and choose the best to choose the ones that suit and meet their own needs!
Folic acid deficiency is different in everyone, and the health of children and mothers is also affected by many factors.
Supplement a variety of nutrients: one is to reduce the risk of various diseases; the other is for the health of the mother and baby.
As long as you are not particularly picky eaters and have no special diseases, you can achieve a good pregnancy preparation effect by eating well, exercising well, sleeping well, and maintaining a beautiful mood.
Childbirth is a major event in a woman's life, in addition to physical, but also mental pressure.
Bacteria hopes that everyone can spend the pregnancy and the time before and after pregnancy in a healthy and comfortable way.
If you think this article is helpful, remember to like and forward, give the bacteria a little support!
Can help everyone solve the problem, is the biggest motivation for the bacteria to continue to move forward!