As long as you can maintain your youth forever, even if you go to the soup and go to the fire. From ancient times to the present, from west to east, many celebrities, nobles, and literati have become crazy because of their desire for immortality: the Qin Emperor has gone mad because of his desire for immortality: the Qin Emperor has cut down the Bald Shu Mountains and built the Afang Palace only to find the immortals to ascend to heaven; the Jiajing Emperor has requisitioned tens of thousands of cardamom maidens and used their menstrual blood to refine cinnabar dan to keep their faces; elizabeth Bartoli, a nobleman in the West, has not hesitated to lure kidnapped young girls to drink their blood and bathe their blood, just to maintain their beauty and appearance, and finally become a "female devil" who has become a color that people smell.
How many people are eager for immortality, youth, and immortality, and do their best but ultimately get nothing, and some even speed up the process of their old age and death due to lack of scientific support. Fortunately, modern scientists have found that the elixir of longevity has always been hidden in our daily lives.
01 Chinese and American scientists find "natural anti-aging substances" in grapes
Recently, scientists from the Chinese Academy of Sciences, together with mayo Medical Center, Buck Institute of Aging and other four top scientific research institutions, released a study: they found a flavonoid substance of proanthocyanidin C1 in a specific grape seed, which can help the body start "autophagy", effectively remove senescent cells and will not affect other normal cells.
The researchers said they screened 45 plant molecules from nearly a thousand natural substances based on the aging mechanism of the cells of the organism, and finally found a substance in a rare grape seed that can "accurately remove senescent cells" PCC1. After intermittent ingestion experiments on natural aging laboratory animals once every 2 weeks, their senescent cells were significantly reduced and the level of inflammation in the body due to aging was also significantly reduced.
In addition to intrinsic indicators such as cells, experimental animals including grip strength, limb sensitivity and neural response speed were positively improved, and the median lifespan was miraculously extended by 64.2%. As soon as the experimental data of riding the dust was released, it attracted the attention of the anti-aging research community at home and abroad, and the cutting-edge science popularization platform "Time School" formed by Fudan University pharmacy students commented in its article: "PCC1 may be the preferred choice of a new generation of natural Senolytics. ”
02 Or the new Senolytics substance
Senolytics has long been considered one of the ways to address the aging of organisms, which can achieve the goal of targeting the elimination of senescent cells by interfering with the signaling pathways of old bad cells and suspending the anti-apoptotic pathways. Spanish scientist López pointed out back in 2013 that too much accumulation of senescent cells would accelerate the aging of organisms, and Senolytics is one of the solutions.
Only because of the previously discovered Senolytics substances, such as dasartinib, there are "cell dependence drawbacks", long-term use may bring cytotoxicity and other issues, this method has not been adopted by the academic community, and PCC1 circumvents this drawback, it is likely to derive a new anti-aging market. There have been such examples in the academic community before: Harvard geneticist David found in the experiment that a natural substance called "nicotinamide single nucleotide" can prolong the life of the time, the United States and Japan and other countries have tracked and developed it, and the current supplement "Palovir Pro" derived from this has reached 10 billion in just 2 years.
In research from the University of Tokyo, Keio University, the University of New South Wales and other top institutions, it has also been confirmed many times that the core substance of "Palovi pro" nicotinamide single nucleotide can help organisms remove necrotic senescent cells in the body, and achieve a number of international old indicators such as mitochondria and telomeres to return to the state of youth and adulthood. Unsurprisingly, PCC1, which is also a natural anti-aging player, is likely to become the next phenomenon-level technology product.
03 Can research and development by research institutions bring about a lifespan change?
The anti-aging research results that appeared in the blowout made the academic community excited. It is reported that in addition to the study found that the natural Senolytics substance PCC1, the team of Professor Liu Guanghui of the Chinese Academy of Sciences also previously conquered some of the human aging codes and found the key enzyme KAT7; and Israeli scientists also confirmed that the o2 ark micro-hyperbaric oxygen chamber can protect telomeres and prolong the survival period as an external instrument.
At present, according to the "Time Pie" news, PCC1 has confirmed in 3 animal experiments that specific doses have no toxic side effects on cells and the survival time during the trial period has been extended. In the later stage, four top institutions such as Mayo Medical Center, Buck, and the Chinese Academy of Sciences will study it in the next step, and the "Time School" will serve as a scientific research platform for the head or organize tasting activities to determine its specific effect in organisms.
At the same time, in the face of the rapid development of biotechnology, some professionals believe that "this may set off an anti-aging trend in China.". Last year's census data pointed out that by 2025, there will be 300 million people over the age of sixty in China, and last year, because of the "anti-aging research bonus of scientific and technological products", Palovie pro" has been favored by dozens of listed companies, and PCC1 may be more popular as a new generation of natural players.
"It's a fact that people are accelerating into the age of 100." A few years ago, when the economist Linda Gratton made such a prediction in the book "100 Years Life", everyone still felt alarmist, but now it is true from the existing technology, and it is faster. And what we need to do now may be to plan our own life for a hundred years.