Source: Xinmin Evening News 2024-06-29 18:29 Shanghai
Japan's Ministry of Health, Labor and Welfare said on the 28th local time that 76 new people died after suspected of taking Kobayashi Pharmaceutical Company's health products containing red yeast rice ingredients. The Ministry of Health, Labor and Welfare said that Kobayashi Pharmaceutical did not report the latest information it had in a timely manner, which is regrettable, and that the Ministry of Health, Labour and Welfare will be directly responsible for future investigations into the deaths.
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According to Japanese media reports on the 28th, the Ministry of Health, Labor and Welfare asked Kobayashi Pharmaceutical on the 13th whether there were any new related deaths, and Kobayashi Pharmaceutical replied that there were none, but on the 14th, it changed its words and said that "there are such cases", but the specific number of people was not reported to the Ministry of Health, Labor and Welfare until the 27th.
According to the press release issued by Kobayashi Pharmaceutical on the 28th, the company received inquiries from the families of 170 deceased consumers, of which 76 deceased had taken the company's red yeast rice health products before their deaths, but whether there was a causal relationship between their deaths and this is still under investigation. According to the communiqué, the direct causes of death of the 76 deceased included not only kidney-related diseases, but also cancer, cerebral infarction, pneumonia and other diseases. The Ministry of Health, Labor and Welfare has instructed Kobayashi Pharmaceutical to report as soon as possible the duration and dosage of the deceased's red yeast rice supplements.
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In recent months, many people in Japan have been hospitalized or even died of kidney disease after taking Kobayashi Pharmaceutical's red yeast rice-containing supplements.
According to Japan's Ministry of Health, Labor and Welfare, as of May 28, five consumers who took Kobayashi Pharmaceutical's red yeast rice-containing health products had died and more than 1,600 people had sought medical attention.
After analyzing the health products and the red yeast rice ingredients used, Kobayashi Pharmaceutical Company found that there were mold-derived ingredients in its self-produced red yeast rice ingredients. Japan's Ministry of Health, Labor and Welfare previously said that Penicillic acid and some other "unexpected substances" were found in the problematic red yeast rice raw materials produced by Kobayashi Pharmaceutical. Researchers are analyzing the specific composition of the substance and why it is present in the red yeast rice raw material.
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Japan's "Internet celebrity medicine" has repeatedly overturned in recent years
Japanese "Internet celebrity" eye drops
In April 2019, several best-selling eye drops from Japan were banned in Canada. According to information released by Health Canada, a total of 6 eye drops and acne treatment creams from Japan have been removed from the shelves, and the specific recall list includes Santen Pharmaceutical's silver package eye drops SanteFXNeo, gold package eye drops SanteFXV+, color package eye drops SanteFXNEO and SantePC eye drops. Health Canada believes that these products contain ingredients that are prescription drugs and should be used under the guidance of a doctor, otherwise they may cause serious side effects and endanger the health of the user.
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Anpanman children's cold syrup
In October 2020, Japan's "Children's Cold Syrup" series of products, which are widely popular in domestic and overseas markets, announced a large-scale recall of about 7.75 million bottles. This is Ikeda Mododo's "Anpanman Children's Cold Syrup", which comes in four flavors, including strawberry and peach, and is easy for children to consume, making it popular among similar products.
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Ikeda Mojodo owns its own pharmaceutical factory, but the children's cold syrup recalled this time is manufactured by a pharmaceutical company called Nissin Pharmaceutical, and the recall is due to the fact that the product did not complete all the quality inspection processes before leaving the factory, and there were omissions in the intermediate links.
EVE "White Rabbit Pain Relief"
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EVE "White Rabbit Pain Relief Tablets" is an over-the-counter drug produced in Japan, which has not been approved for marketing in mainland China and is mainly sold online. In fact, the main ingredients of this medicine that have an analgesic effect are the same as the common domestic drugs Fenpide and ibuprofen, which are all ibuprofen. In addition to ibuprofen, EVE's "White Rabbit Pain Relief Tablets" also use two ingredients: valproyl urea and caffeine. The survey found that valproylurea has been eliminated in many countries. It cannot be used as a pharmaceutical ingredient or medicinal use in the mainland, and can only be traded as a chemical ingredient for scientific research.
When valproylurea enters the body, it binds to platelets, forming a complex of drugs and antibodies, and when the drug is removed from the body, the platelets are also removed, causing idiopathic thrombocytopenic purpura. In addition, valproyl urea itself has a certain degree of dependence and addiction. Although these drugs are not available in prescription in Japan, the risks of taking them are uncontrollable.
Taisho cold medicine
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Photo/Taisho Cold Medicine Gold A Granules "Taisho Cold Medicine" official website
Known as "one pack is good, two packs are consolidated, every family must have" Taisho cold medicine gold A granules, experts from the Department of Pharmacy of the First Hospital of Zhejiang University found that Taizheng cold medicine contains 9 kinds of ingredients, which are basically not seen in domestic cold medicine prescriptions.
"It seems that the more ingredients, the better the effect, but in fact, many ingredients in cold medicine only relieve the symptoms of various discomforts, but do not shorten the course of the cold." Experts from the Department of Pharmacy of the First Hospital of Zhejiang University said that when a cold occurs, the corresponding ingredients should be selected according to the symptoms, and the excess ingredients only have side effects for the human body.
Ryukakusan cough tablets
The Japanese "miracle medicine" Ryukakusan is also popular with purchasing agents, and the cough tablets of its strong cough suppressant series under its brand are "similar" to Taisho cold medicine. According to experts from the Department of Pharmacy of the First Hospital of Zhejiang University, Longjiaosan cough tablets contain 9 ingredients (or extracts), of which dihydrocodeine phosphate, racemic ephedrine hydrochloride, and anhydrous caffeine are the same as those of Taisho cold medicine.
"We analyzed the ingredients of Western medicine in Ryukakusan against the list of common ingredients of cold medicines and found that in addition to not having the effect of lowering body temperature, the various ingredients of Ryukakusan cough tablets surrounded the common symptoms of colds, and the cough suppressant ingredients in them can be described as very bold." Experts from the Department of Pharmacy of the First Hospital of Zhejiang University said that Longjiaosan cough tablets have both dihydrocodeine phosphate with central antitussive effect and nacodine with peripheral antitussive effect, and this prescription almost does not exist in domestic medicine.
Xinmin Evening News (xmwb1929) integrates CCTV news, China Consumer Daily, and overseas network
Editor: Gong Zijun
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